Results 21 to 30 of about 562,414 (215)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Metabolic contributions to hamstring muscle damage during maximal, high‐speed eccentric exercise in males

Physiological Reports
High‐velocity eccentric training elicits exercise‐induced muscle damage (EIMD), predominantly attributed to mechanical strain. However, the potential contribution of metabolic stress to muscle damage remains underexplored, especially in trained ...
Carsten Schwiete, Joachim Mester, Patrick Wahl, Holger Broich, Michael Behringer   +4 more
doaj   +1 more source

The effect of taurine supplementation on markers of muscle damage and muscle pain in an athletic population: A systematic review and meta-analysis of randomized controlled trials assessed using the grading of recommendations, assessment, development, and evaluation approach

Heliyon
Background: Moderate to intense physical activity is vital for health but may lead to exercise-induced muscle damage (EIMD) and muscle pain. Taurine supplementation (TS) is used to aid post-exercise recovery.
Elaheh Dehghani, Fatemeh Naeini, Sakineh Shab Bidar, Mohammad Beba, Erfan Mortezapour, Ruhollah Nourian, Khashayar Danandeh, Zahra Gohari Dezfuli, Kurosh Djafarian   +8 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Clinical Outcomes of Bipolar Hemiarthroplasty with a Conjoined Tendon-Preserving Posterior Approach for Femoral Neck Fractures

Medicina
Background and Objectives: The conventional posterior approach in the lateral decubitus position is widely used for femoral neck fractures in femoral hemiarthroplasty. Postoperative dislocation is the major problem with this approach.
Hidetatsu Tanaka, Yu Mori, Atsushi Noro, Toshihisa Yano, Toshimi Aizawa, Keiji Masuda   +5 more
doaj   +1 more source

Transgenic overexpression of heat shock protein 72 in mouse muscle protects against exhaustive exercise-induced skeletal muscle damage

Journal of the Formosan Medical Association, 2013
Lifelong overexpression of heat shock protein (HSP) 72 in skeletal muscle is known to protect against age-related oxidative stress and muscle damage. This study aimed to ascertain whether exhaustive exercise (EE)-induced muscle fatigue and damage can be ...
Chieh-Chung Liu, Cheng-Hsien Lin, Chuan-Yi Lin, Ching-Cheng Lee, Mao-Tsun Lin, Hsiao-Chuan Wen   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Effects of cumulative school soccer matches separated by 24-h or 48-h interval on physical recovery status of U-19 players

Revista Brasileira de Cineantropometria e Desempenho Humano, 2021
This study aimed to evaluate the effects of cumulative school soccer matches separated by 24-h or 48-h intervals on recovery status of U-19 players. Thirty-four school athletes (17.6 ± 1.1 years) who played an U-19 school soccer competition (composed of ...
Vitor Hugo Santos Rezende, Diego A. Borba, Lucas A. Souza, Suene F. N. Chaves, Maria H. A. Pinheiro, Hugo C. Martins Costa, Daniel B. Coelho, Rauno A. P. Simola, Carlos M. A. Costa, André Bonadias Gadelha   +9 more
doaj