Annals of Neurology, EarlyView.Objective To evaluate the effectiveness and safety of ocrelizumab in self‐identified black and Hispanic people with relapsing multiple sclerosis. Methods The Characterization of Ocrelizumab in Minorities with Multiple Sclerosis (CHIMES) trial, a prospective, open‐label, single‐arm, phase 4 study, intentionally recruited underrepresented populations in ...
Lilyana Amezcua +16 more
wiley +1 more source
Machine Learning-Driven Muscle Fatigue Estimation in Resistance Training with Assistive Robotics. [PDF]
Sensors (Basel)Baek JY, Kwon JH, Khan H, Lee MC.
europepmc +1 more source
Three‐dimensional geometric morphometric analysis of diaphragmatic dome motion in COPD patients
The Anatomical Record, EarlyView.Abstract Diaphragmatic dysfunction is a hallmark of chronic obstructive pulmonary disease (COPD), especially in emphysema, where hyperinflation alters diaphragm geometry and impairs inspiratory mechanics. However, quantitative three‐dimensional (3D) assessments of diaphragmatic dome shape and motion across COPD phenotypes are limited.
José M. López‐Rey +5 more
wiley +1 more source
On the effectiveness of rehabilitative exercise training in COPD: why does contractile muscle fatigue matter? [PDF]
ERJ Open ResMarillier M.
europepmc +1 more source
The 9+ month marathon: How pregnancy may have shaped human endurance capacities
The Anatomical Record, EarlyView.Abstract Anthropology has long considered the evolution of our uniquely human endurance capacities to be the result of selection upon anatomical and physiological features imposed by the demands of thermoregulation and resource acquisition, particularly during the demands of persistence hunting. Research has focused on the anatomical changes present in
Cara Ocobock
wiley +1 more source
Identification of lower limb muscle fatigue in basketball players based on sEMG signals. [PDF]
Front PhysiolMa X, Chen S, Li Q.
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The compensatory interaction between motor unit firing behavior and muscle force during fatigue.
Journal of Neurophysiology, 2016 Paola Contessa +2 more
semanticscholar +1 more source
The fossil record stays silent: Confusions and conundrums for hominin pelvis evolution
The Anatomical Record, EarlyView.Abstract The evolution of the hominin pelvis is commonly modeled as a series of stages driven largely by the requirements of bipedal locomotion, reproduction, thermoregulation, and pelvic floor muscular support. These patterns are complicated by variation in canal dimensions in relationship with different changes in overall pelvic breadths. To quantify
Helen K. Kurki, Cara M. Wall‐Scheffler
wiley +1 more source
HUWE1 in Skeletal Muscle Prevents Muscle Fatigue via Maintaining Iron and Calcium Homeostasis. [PDF]
Adv Sci (Weinh)Jiao H +10 more
europepmc +1 more source
The pelvis doesn't walk by itself: Wider pelves reduce the cost of walking over unstable surfaces
The Anatomical Record, EarlyView.Abstract Walking over variable and/or unstable terrain is a key aspect of daily life and was crucial to the evolution of bipedalism. The ability to find gait solutions that maintained stability over uneven terrain for the least increase in metabolic cost was likely a hallmark of locomotor effectiveness in early humans, in particular acting as an ...
Cara Wall‐Scheffler +2 more
wiley +1 more source