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Function and Fatigue of Respiratory Muscles

Chest, 1985
The functional anatomy of the respiratory muscles and their actions and interactions are presented, particularly of the diaphragm. The large amount of blood flow to respiratory muscles and the determination of blood flow are reviewed, while the role these muscles play in the overall economy of the body in health and disease are discussed.
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No Muscle Is an Island

Medicine & Science in Sports & Exercise, 2016
Muscle fatigue has been studied with a variety approaches, tools and technologies. The foci of these studies have ranged tremendously, from molecules to the entire organism. Single cell and animal models have been used to gain mechanistic insight into the fatigue process.
Kent, Jane A   +4 more
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Fatigue Effects on Muscle Excitability

International Journal of Sports Medicine, 1996
Repeated isometric or shortening contractions of skeletal muscle cause muscle fatigue but several prior studies have reported an apparent absence of muscle fatigue when humans performed up to 70 lengthening contractions. We pursued the hypothesis that perhaps muscle excitability is a factor that aids force preservation with repeated eccentric actions ...
T, Hortobágyi   +3 more
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Change in manipulation with muscle fatigue

European Journal of Neuroscience, 2010
AbstractMuscle fatigue is defined as an exercise‐induced reduction in the force‐generating capacity of muscle. Here, we investigated the effect of muscle fatigue on hand dexterity. Healthy adults (n = 17) gripped and lifted an object (0.342 kg) five times before and after two interventions.
Gabrielle, Todd   +2 more
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Muscle Fatigue: The Role of Metabolism

Canadian Journal of Applied Physiology, 2002
This paper examined the role of metabolites in causing muscle fatigue. Previous studies have shown that Pi [Formula: see text] and H+ may be important factors in causing fatigue. A key question is the potential interaction between metabolic end-products and calcium related excitation-contraction coupling fatigue (ECC).
Kevin K, McCully   +3 more
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Neuromuscular Fatigue in Dystrophic Muscle

Nature, 1962
THE effects of the dystrophic process upon muscle function are of continued interest. Dystrophic mouse muscle has been found to exhibit multiple action potentials, spontaneously, as well as in response to a single stimulus to its nerve1,2; d-tubocurarine or sustained, periodic single shock stimulation shortens the after-discharges1.
Conrad, J T, Glaser, G H
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Measurement of human muscle fatigue

Journal of Neuroscience Methods, 1997
Human muscle fatigue has been studied using a wide variety of exercise models, protocols and assessment methods. Based on the definition of fatigue as 'any reduction in the maximal capacity to generate force or power output', the different methods to measure fatigue are discussed.
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Are the antagonist muscles fatigued during a fatigue task of agonist muscles?

Isokinetics and Exercise Science, 2004
The purpose of this study was to examine if a fatigue task of agonist muscles also causes fatigue to the antagonist muscles. Fourteen(n = 14) healthy males (age: 24.3 ± 2.5 y) participated in two isokinetic fatigue protocols (IFPs) at the angular velocity of 60°/s. The motion ranged from 0° to 90° of knee flexion.
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Muscle Fatigue: The Cellular Aspects

The American Journal of Sports Medicine, 1996
High-intensity contractile activity causes a rapid fall in peak tension or force, a reduced shortening velocity, decline in power, prolonged twitch duration, a sarcolemma action potential with a prolonged duration, reduced amplitude, and a conduction velocity that may result in conduction block.
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The muscle fatigue fiber model

Mathematics and Computers in Simulation, 2010
The aim of this study was to integrate the effect of muscle fatigue into the skeletal muscle fiber model, which was previously developed in our laboratory and was based on the modified Huxley equation with the calcium activation taken into account. The cellular mechanisms such as (i) the attachment of myosin heads to the actin binding sites, (ii) the ...
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