Results 131 to 140 of about 1,226,791 (296)
Advanced Materials, EarlyView.In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren +6 more
wiley +1 more source
A Noninvasive Approach to Study Localized Forces in 3D Epithelia
Advanced Materials, EarlyView.Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand +9 more
wiley +1 more source
Single muscle fibre contractile function with ageing. [PDF]
J Physiol, 2022 Grosicki GJ, Zepeda CS, Sundberg CW.
europepmc +1 more source
Variability in muscle fibre areas in whole human quadriceps muscle : How much and why?
, 1989 To determine the variability in fibre areas in the human vastus lateralis muscle, cross-sections (15 microns) of whole autopsied muscles from eight young men have been prepared, and the cross-sectional area (CSA) of 375 type 1 and 375 type 2 fibres has ...
Lexell, Jan, Taylor, CC
core +1 more source
A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration
Advanced Materials Interfaces, EarlyView.The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani +2 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina +5 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.Transparent microelectrode arrays enable simultaneous optical and electrical electrophysiology with high spatiotemporal resolution, allowing multimodal observations of dynamic biological systems. Advances in materials and device architectures improve device performance by addressing key trade‐offs between optical transparency, impedance, and ...
Michael Abraham Listyawan +6 more
wiley +1 more source
A comparative proteomics approach to studying skeletal muscle mitochondria from myostatin knockout mice [PDF]
, 2006 Myostatin is a negative regulator of muscle growth. When it is not present or non-functional double-muscling occurs, the primary characteristic of this phenotype being an increase in muscle mass.
Puddick, Jonathan
core
Advanced Materials Technologies, EarlyView.A multi‐point oxygen‐sensing ultra‐fine needle (MO‐UFN) is developed by conformally integrating a lithographically patterned flexible electrochemical sensor array onto a clinical acupuncture needle. The platform preserves an approximately 0.3 mm diameter while enabling spatially resolved oxygen profiling along the insertion pathway.
Yeju Seo +9 more
wiley +1 more source
3D‐Printed Actuator Powered by Liquid Crystal Elastomer Muscles at the Water–Air Interface
Advanced Materials Technologies, EarlyView.Soft robots for unstructured environments require responsive, durable actuators. Liquid crystal elastomers (LCEs) provide large reversible deformations under thermal or optical stimuli. Direct ink writing enables fabrication of LCE actuators integrated with silicone, with mesogen chemistry and oligomers optimized for printable inks.
Cecilie Ryberg +5 more
wiley +1 more source