Results 41 to 50 of about 2,038,349 (282)

RNAseq analysis of fast skeletal muscle in restriction-fed transgenic coho salmon (Oncorhynchus kisutch) : an experimental model uncoupling the growth hormone and nutritional signals regulating growth [PDF]

, 2015
Background Coho salmon (Oncorhynchus kisutch) transgenic for growth hormone (Gh) express Gh in multiple tissues which results in increased appetite and continuous high growth with satiation feeding. Restricting Gh-transgenics to the same lower ration (TR)
Devlin, Robert, Robert H Devlin, Johnston, Ian Alistair, Daniel Garcia de la serrana, Ian A Johnston, Garcia de la Serrana Castillo, Daniel, Johnston, Ian Alistair; id_orcid   +6 more
core   +1 more source

AAV1.NT‐3 gene therapy in the SOD1KO mouse model of accelerated sarcopenia

Journal of Cachexia, Sarcopenia and Muscle, 2023
Background Sarcopenia, an age‐related loss of muscle mass, is a critical factor that affects the health of the older adults. The SOD1KO mouse is deficient of Cu/Zn superoxide dismutase, used as an accelerated aging model.
Lingying Tong, Burcak Ozes, Kyle Moss, Morgan Myers, Alicia Ridgley, Zarife Sahenk   +5 more
doaj   +1 more source

Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. II -Genetic factors related to animal performance and advances in methodology [PDF]

, 2011
Selective breeding is an effective tool to improve livestock. Several selection experiments have been conducted to study direct selection responses as well as correlated responses in traits of skeletal muscle growth and function. Moreover, comparisons of
Wimmers, K, Te Pas, M. F. W., N. Oksbjerg, Te Pas, M. F.W., Stickland, N C, Oksbjerg, Neils, Rehfeldt, C., Stickland, Neil, Rehfeldt, Charlotte, Brameld, J M, Picard, Brigitte, B., Te Pas, Marinus, Pas, M, Nissen, P M, Power, D M, Valente, L M P, K. Wimmers, Oksbjerg, N, Nissen, Pia, Wimmers, Klaus, Valente, L.M.P., Brameld, J. M., M.F.W. Te Pas, Picard, B., Stickland, N.C., Pas, M.F.W., te, Berri, C., Picard, B, Nissen, P. M., B. Picard, Stickland, N. C., Berri, C, Rehfeldt, C, P.M. Nissen, Valente, L. M.P., Valente, Luísa, Power, Deborah, Brameld, John, Nissen, P.M., Brameld, J.M., C. Rehfeldt, Wimmers, K., N.C. Stickland, Power, D. M., C. Berri, D.M. Power, Valente, L. M. P., J.M. Brameld, Power, D.M., L.M.P. Valente, Berri, Cécile, Oksbjerg, N., Picard, Brigitte,   +52 more
core   +1 more source

Muscle diffusion MRI reveals autophagic buildup in a mouse model for Pompe disease

Scientific Reports, 2023
Quantitative muscle MRI is increasingly important in the non-invasive evaluation of neuromuscular disorders and their progression. Underlying histopathotological alterations, leading to changes in qMRI parameters are incompletely unraveled.
Marlena Rohm, Gabriele Russo, Xavier Helluy, Martijn Froeling, Vincent Umathum, Nicolina Südkamp, Denise Manahan-Vaughan, Robert Rehmann, Johannes Forsting, Frank Jacobsen, Andreas Roos, Yoon Shin, Anne Schänzer, Matthias Vorgerd, Lara Schlaffke   +14 more
doaj   +1 more source

Advances in research on the prenatal development of skeletal muscle in animals in relation to the quality of muscle-based food. I - Regulation of myogenesis and environmental impact [PDF]

, 2010
Skeletal muscle development in vertebrates – also termed myogenesis – is a highly integrated process. Evidence to date indicates that the processes are very similar across mammals, poultry and fish, although the timings of the various steps differ ...
Wimmers, K, Te Pas, M. F. W., N. Oksbjerg, Te Pas, M. F.W., Stickland, N C, Rehfeldt, C., Stickland, Neil, Rehfeldt, Charlotte, Oksbjerg, Niels, Brameld, J M, Picard, Brigitte, B., Pas, M, Nissen, P M, Power, D M, Valente, L M P, K. Wimmers, Oksbjerg, N, Nissen, Pia, Wimmers, Klaus, Valente, L.M.P., Brameld, J. M., M.F.W. Te Pas, Picard, B., Stickland, N.C., Pas, M.F.W., te, Berri, C., Picard, B, Nissen, P. M., B. Picard, Stickland, N. C., Berri, C, Rehfeldt, C, P.M. Nissen, Valente, L. M.P., Valente, Luísa, Power, Deborah, Brameld, John, Nissen, P.M., Brameld, J.M., C. Rehfeldt, Wimmers, K., N.C. Stickland, Power, D. M., C. Berri, D.M. Power, Valente, L. M. P., J.M. Brameld, Power, D.M., L.M.P. Valente, Berri, Cécile, Oksbjerg, N., Picard, Brigitte,, Te pas, Marinus   +52 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

The eccentric mechanotransduction, neuro-muscular transmission, and structural reversibility of muscle fatty infiltration. An experimental advanced disuse muscle-wasting model of rabbit supraspinatus

Archives of Medical Science, 2021
Introduction Full-thickness rotator cuff tear is present in almost 50% of patients over age 65 years, and its degree is known to be a good predictor of the severity of muscle-wasting (MW) sarcopaenia, also known as fatty degeneration (FD). A FD CT grade >
Jarosław Fabiś, Marian Danilewicz, Kryspin R. Niedzielski, Michał Waszczykowski, Anna Fabiś-Strobin, Andrzej Bogucki   +5 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Usage of a localised microflow device to show that mitochondrial networks are not extensive in skeletal muscle fibres. [PDF]

PLoS ONE, 2014
In cells, such as neurones and immune cells, mitochondria can form dynamic and extensive networks that change over the minute timescale. In contrast, mitochondria in adult mammalian skeletal muscle fibres show little motility over several hours. Here, we
Joseph Bruton, Gavin D M Jeffries, Håkan Westerblad   +2 more
doaj   +1 more source

Meat quality of the Berrichon du Cher lambs and its cross-breeds with a native breed

Ciência Rural, 2022
: This study evaluated the meat of lambs from crossbreeding of Polish lowland sheep, heather and rams of the Berrichone du Cher breed (B). The lambs were kept in a medium-intensive feeding system.
Elżbieta Horoszewicz, Roman Niedziółka   +1 more
doaj   +1 more source