Results 251 to 260 of about 1,793,126 (357)

Stem Cell Secretome Treatment Reduces Adiposity and Improves Glucose Handling During Obesity and Weight Loss in Mice

open access: yesObesity, EarlyView.
ABSTRACT Objective In this study, we investigated the effects of a stem cell‐derived secretome product on adiposity and tissue quality and insulin and glucose levels in obese mice and those undergoing dietary weight loss. Methods Following 16 weeks of high fat diet mice received acute (4 weeks) biweekly intramuscular injections with vehicle or ...
Zachary J. Fennel   +11 more
wiley   +1 more source

Age‐Dependent Correlation of Pulmonary Function Impairment and Aortic Arch Stiffness in Mice

open access: yesPediatric Discovery, EarlyView.
This study examined the relationship between aortic arch stiffness and lung function in aging mice. Multiple linear regression modeling showed moderate to strong correlations between the rise in aortic arch stiffness and changes in lung function as the mice progressively aged.
Ayman Isbatan   +10 more
wiley   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto   +2 more
wiley   +1 more source

Focal extracorporeal shockwave therapy in shoulder calcific tendinopathy: A retrospective observational study of sonographic prognostic factors

open access: yesPM&R, EarlyView.
Abstract Objective To assess the potential prognostic role of sonographic parameters such as glenohumeral joint effusion, subacromial‐subdeltoid bursitis, and the type of intratendinous calcific deposition to predict the clinical and functional outcomes of focal extracorporeal shockwave therapy (fESWT) in patients with calcific tendinopathy of the ...
Arianna Pesaresi   +6 more
wiley   +1 more source

Impact of Lipid Profile Alterations on the Right Heart Function and Prognosis in Pre‐Capillary Pulmonary Hypertension Patients: A Prospective Cohort Study

open access: yesRespirology, EarlyView.
This study found that reduced HDL‐C correlates with impaired RV systolic function and RA strain, highlighting a mechanistic link between lipid abnormalities and right heart remodelling. Additionally, decreased HDL‐C and LDL‐C were identified as independent mortality predictors in precPH patients. Integrating lipid parameters into ESC and ESC‐CMR models
Jiajun Guo   +14 more
wiley   +1 more source

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