Results 81 to 90 of about 779,091 (316)

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa   +10 more
wiley   +1 more source

Ultrasound measurements of gastrocnemius muscle thickness in older people with sarcopenia

open access: yesClinical Interventions in Aging, 2018
Jing Wang, Ying Hu, Guo Tian Department of Ultrasound, The First Affiliated Hospital, Medical College, Zhejiang University, Hangzhou, Zhejiang 310003, China Background: Sarcopenia, defined as low muscle mass and low muscle strength and/or low physical ...
Wang J, Hu Y, Tian G
doaj  

Study on improving muscle mass and endurance in adults

open access: yesAnnals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement
Improving muscle mass is essential for maintaining health and functional capacity in adults. Strength and endurance training are recognized methods for improving these aspects, having significant benefits on general health and quality of life.
Scheuleac Adelina   +1 more
doaj   +1 more source

Development of a Personalized Visualization and Analysis Tool to Improve Clinical Care in Complex Multisystem Diseases With Application to Scleroderma

open access: yesArthritis Care &Research, EarlyView.
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim   +18 more
wiley   +1 more source

Hyperammonemia results in reduced muscle function independent of muscle mass

open access: yesAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 2016
The mechanism of the nearly universal decreased muscle strength in cirrhosis is not known. We evaluated whether hyperammonemia in cirrhosis causes contractile dysfunction independent of reduced skeletal muscle mass. Maximum grip strength and muscle fatigue response were determined in cirrhotic patients and controls.
John, McDaniel   +7 more
openaire   +3 more sources

Adipokines and Associations With Incident Osteoporotic Fracture in Patients With Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, and fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker   +9 more
wiley   +1 more source

Blocking myostatin: muscle mass equals muscle strength? [PDF]

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2020
Markus S. Anker   +2 more
openaire   +3 more sources

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