Comparative Skeletal Muscle Proteomics Using Two-Dimensional Gel Electrophoresis
Proteomes, 2016 The pioneering work by Patrick H. O’Farrell established two-dimensional gel electrophoresis as one of the most important high-resolution protein separation techniques of modern biochemistry (Journal of Biological Chemistry 1975, 250, 4007–4021).
Sandra Murphy +2 more
doaj +1 more source
Metabolites, 2016 Muscle weakness in corticosteroid myopathy is mainly the result of the destruction and atrophy of the myofibrillar compartment of fast-twitch muscle fibers.
Teet Seene, Priit Kaasik
doaj +1 more source
Mechanical oscillations at the cellular scale [PDF]
arXiv, 2001 Active phenomena which involve force generation and motion play a key role in a number of phenomena in living cells such as cell motility, muscle contraction and the active transport of material and organelles. Here we discuss mechanical oscillations generated by active systems in cells. Examples are oscillatory regimes in muscles, the periodic beating
arxiv
Isolation of a new high molecular weight protein associated with desmin and vimentin filaments from avian embryonic skeletal muscle [PDF]
, 1982 Filaments with a diameter of 80-120 Å have been prepared from 14-d-old chick embryonic skeletal muscle, using a physiological salt solution and gel filtration chromatography.
Breckler, Jennifer, Lazarides, Elias
core +2 more sources
The Energy Sensor AMPK: Adaptations to Exercise, Nutritional and Hormonal Signals [PDF]
Spiegelman B. Hormones, Metabolism and the Benefits of Exercise,
Hormones, Metabolism and the Benefits of Exercise, Springer, pp.13-24, 2018,
Research and Perspectives in Endocrine Interactions, 978-3-319-72789-9, 2019 To sustain metabolism, intracellular ATP concentration must be regulated within an appropriate range. This coordination is achieved through the function of the AMP-activated protein kinase (AMPK), a cellular "fuel gauge" that is expressed in essentially all eukaryotic cells as heterotrimeric complexes containing catalytic $\alpha$ subunits and ...
arxiv
Longitudinal RNA-Seq analysis of acute and chronic neurogenic skeletal muscle atrophy. [PDF]
, 2019 Skeletal muscle is a highly adaptable tissue capable of changes in size, contractility, and metabolism according to functional demands. Atrophy is a decline in mass and strength caused by pathologic loss of myofibrillar proteins, and can result from ...
Coppola, Giovanni +4 more
core
The Corepressor NCoR1 Antagonizes PGC-1α and Estrogen-Related Receptor α in the Regulation of Skeletal Muscle Function and Oxidative Metabolism [PDF]
, 2012 Skeletal muscle exhibits a high plasticity and accordingly can quickly adapt to different physiological and pathological stimuli by changing its phenotype largely through diverse epigenetic mechanisms.
Pérez-Schindler, Joaquín +9 more
core +5 more sources
HMACA: Towards Proposing a Cellular Automata Based Tool for Protein Coding, Promoter Region Identification and Protein Structure Prediction [PDF]
International Journal of Research in Computer Applications &
Information Technology, Volume 1, Issue 1, July-September, 2013, pp. 26-31, 2014 Human body consists of lot of cells, each cell consist of DeOxaRibo Nucleic Acid (DNA). Identifying the genes from the DNA sequences is a very difficult task. But identifying the coding regions is more complex task compared to the former. Identifying the protein which occupy little place in genes is a really challenging issue.
arxiv
Rigidity and flexibility in protein-protein interaction networks: a case study on neuromuscular disorders [PDF]
arXiv, 2014 Mutations in proteins can have deleterious effects on a protein's stability and function, which ultimately causes particular diseases. Genetically inherited muscular dystrophies (MDs) include several genetic diseases, which cause increasing weakness in muscles and disability to perform muscular functions progressively.
arxiv
Downhill exercise alters immunoproteasome content in mouse skeletal muscle [PDF]
, 2017 Content of the immunoproteasome, the inducible form of the standard proteasome, increases in atrophic muscle suggesting it may be associated with skeletal muscle remodeling.
Baumann, Cory W. +3 more
core +1 more source