Results 121 to 130 of about 7,838,731 (404)

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

In vitro protein expression profile of cultivated muscle cells from Labeo rohita

Scientific Reports
A new cell line developed from the muscle tissue of L. rohita (LR) was utilized to understand the proteome in-depth. Comparative proteome analysis was performed for LR muscle cells at different passages (1, 15 and 25) using label free quantitative ...
B. S. Yashwanth, Nevil Pinto, A. Sathiyanarayanan, Kiran D. Rasal, S. Sanjeeva, Michael Saad, Reza Ovissipour, David L. Kaplan, Mukunda Goswami   +8 more
doaj   +1 more source

Membrane glucocorticoid receptors are localised in the extracellular matrix and signal through the MAPK pathway in mammalian skeletal muscle fibres [PDF]

, 2015
A number of studies have previously proposed the existence of glucocorticoid receptors on the plasma membrane of many cell types including skeletal muscle fibres.
Dietmar Steverding, Eugene Akujuru, Feliciano Protasi, Gabriel Mutungi, Goldberg AL, Lewis Arthurton, Simona Boncompagni, Timothy Pearson, Wing SS   +8 more
core   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction

Journal of Cachexia, Sarcopenia and Muscle, 2020
Background Cachexia is the direct cause of at least 20% of cancer‐associated deaths. Muscle wasting in skeletal muscle results in weakness, immobility, and death secondary to impaired respiratory muscle function. Muscle proteins are massively degraded in
Thomas Kunzke, Achim Buck, Verena M. Prade, Annette Feuchtinger, Olga Prokopchuk, Marc E. Martignoni, Simone Heisz, Hans Hauner, Klaus‐Peter Janssen, Axel Walch, Michaela Aichler   +10 more
doaj   +1 more source

Identification of mouse soleus muscle proteins altered in response to changes in gravity loading. [PDF]

Sci Rep, 2023
Ino Y, Ohira T, Kumagai K, Nakai Y, Akiyama T, Moriyama K, Takeda Y, Saito T, Ryo A, Inaba Y, Hirano H, Kimura Y.   +11 more
europepmc   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Editorial: Quality and nutrition of meat and meat products: emphasis on muscle protein structure, activity, modification, and functionality

Frontiers in Nutrition, 2023
Rui Liu, Tong Xing
doaj   +1 more source

Altered cross-bridge properties in skeletal muscle dystrophies

Frontiers in Physiology, 2014
Force and motion generated by skeletal muscle ultimately depends on the cyclical interaction of actin with myosin. This mechanical process is regulated by intracellular Ca2+ through the thin filament-associated regulatory proteins i.e.; troponins and ...
Aziz eGuellich, Aziz eGuellich, Elisa eNegroni, Elisa eNegroni, Elisa eNegroni, Elisa eNegroni, Valérie eDecostre, Alexandre eDemoule, Alexandre eDemoule, Alexandre eDemoule, Alexandre eDemoule, Catherine eCoirault, Catherine eCoirault, Catherine eCoirault, Catherine eCoirault   +14 more
doaj   +1 more source

Selective precipitation reaction: a novel diagnostic test for tissue pathology in Atlantic Salmon, Salmo salar, infected with Salmonid Alpha-Virus (SAV3) [PDF]

, 2017
While investigating biomarkers for infection with salmonid alphavirus (SAV), the cause of pancreas disease (PD), a selective precipitation reaction (SPR) has been discovered in serum which could be an on-farm qualitative test and an in-laboratory ...
Adams, Asenjo, Biacchesi, Braceland, Braceland, Braceland, Ceciliani, Coeurdacier, Cray, Dawson, Heide, Kibenge, Larsson, Lerfall, Mayeux, McLoughlin, McLoughlin, Mcloughlin, McVicar, Munro, Taksdal   +20 more
core   +1 more source