Results 1 to 10 of about 1,552,624 (372)

Muscle relaxant use and the associated risk of incident frailty in patients with diabetic kidney disease: a longitudinal cohort study [PDF]

Therapeutic Advances in Drug Safety, 2021
Background: Patients with diabetic kidney disease (DKD) are at an increased risk of frailty. The exposure to muscle relaxants frequently leads to adverse effects despite their modest therapeutic efficacy, but whether muscle relaxants predispose users to ...
Szu-Ying Lee, Jui Wang, Hung-Bin Tsai, Chia-Ter Chao, Kuo-Liong Chien, Jenq-Wen Huang   +5 more
doaj   +3 more sources

Azemiopsin, a Selective Peptide Antagonist of Muscle Nicotinic Acetylcholine Receptor: Preclinical Evaluation as a Local Muscle Relaxant [PDF]

Toxins, 2018
Azemiopsin (Az), a linear peptide from the Azemiops feae viper venom, contains no disulfide bonds, is a high-affinity and selective inhibitor of nicotinic acetylcholine receptor (nAChR) of muscle type and may be considered as potentially applicable ...
Irina V. Shelukhina, Maxim N. Zhmak, Alexander V. Lobanov, Igor A. Ivanov, Alexandra I. Garifulina, Irina N. Kravchenko, Ekaterina A. Rasskazova, Margarita A. Salmova, Elena A. Tukhovskaya, Vladimir A. Rykov, Gulsara A. Slashcheva, Natalya S. Egorova, Inessa S. Muzyka, Victor I. Tsetlin, Yuri N. Utkin   +14 more
doaj   +3 more sources

Identification of a novel starfish neuropeptide that acts as a muscle relaxant [PDF]

J Neurochem, 2016
Neuropeptides that act as muscle relaxants have been identified in chordates and protostomian invertebrates but little is known about the molecular identity of neuropeptides that act as muscle relaxants in deuterostomian invertebrates (e.g.
Elphick, MR, Go, H-J, Kim, C-H, Kim, EJ, Lin, M, Oh, HY, Park, NG   +6 more
core   +3 more sources

Evidence Supports Tradition: The in Vitro Effects of Roman Chamomile on Smooth Muscles [PDF]

Frontiers in Pharmacology, 2018
The dried flowers of Chamaemelum nobile (L.) All. have been used in traditional medicine for different conditions related to the spasm of the gastrointestinal system.
Zsolt Sándor, Javad Mottaghipisheh, Katalin Veres, Judit Hohmann, Tímea Bencsik, Attila Horváth, Dezső Kelemen, Róbert Papp, Loránd Barthó, Dezső Csupor, Dezső Csupor   +10 more
doaj   +3 more sources

Relaxant effect of Curcuma longa on rat tracheal smooth muscle and its possible mechanisms

Pharmaceutical Biology, 2017
Context: Turmeric is a spice obtained from the root of Curcuma longa L. (Zingiberaceae) with anti-aging, anticancer, anti-Alzheimer’s disease, antioxidant and other medicinal properties. Objective: The relaxant effect of C.
Bahman Emami, Farzaneh Shakeri, Vahideh Ghorani, Mohammad Hossein Boskabady   +3 more
doaj   +2 more sources

Antinociceptive, muscle relaxant and sedative activities of gold nanoparticles generated by methanolic extract of Euphorbia milii [PDF]

BMC Complementary and Alternative Medicine, 2015
BackgroundNanotechnology has potential future for enhancing therapeutic efficacy and reducing the unwanted effects of herbal drugs. The biological research on Euphorbia species has been supported by the use of some plants in traditional medicines.
Nazar Ul Islam, Ibrahim Khan, Abdur Rauf, Naveed Muhammad, Muhammad Shahid, Muhammad Raza Shah   +5 more
openalex   +2 more sources

The ultrasound-guided nerve blocks of abdominal wall contributed to anesthetic management of cholecystectomy in a patient with Becker muscular dystrophy without using muscle relaxants [PDF]

JA Clinical Reports, 2017
Becker muscular dystrophy (BMD) is a progressive neuromuscular disorder caused by mutations in the dystrophin gene. The sensitivity to non-depolarizing muscle relaxant in a patient with muscle dystrophy is reportedly higher than that in normal ...
Masato Iwata, Naoya Kuzumoto, Yuka Akasaki, Masayo Morioka, Kana Nakayama, Nobuyoshi Matsuzawa, Katsuhiro Kimoto, Toshiyuki Shimomura   +7 more
doaj   +2 more sources

Muscle Relaxant and Sedative-Hypnotic Activities of Extract of Viola betonicifolia in Animal Models Supported by Its Isolated Compound, 4-Hydroxy Coumarin

Journal of Chemistry, 2013
The crude methanolic extract of the whole plant of Viola betonicifolia (VBME) was investigated for anxiolytic, muscle relaxant, sleep induction, antidepressant, and sedative activities) to ascertain its scientific values.
Naveed Muhammad, Mohammad Saeed, Haroon Khan, Achyut Adhikari, Khalid Mohammed Khan   +4 more
doaj   +2 more sources

Basic aspects of the pharmacodynamics of tolperisone, a widely applicable centrally acting muscle relaxant [PDF]

, 2014
Tolperisone (2-methyl-1-(4-methylphenyl)-3-piperidin-1-ylpropan-1-one hydro-chloride) was introduced in the clinical practice more than forty years ago and is still evaluated as a widely applicable compound in pathologically elevated skeletal muscle tone
Bajaj P, Dulin J, Farkas S, Fels G, Fujioka M, Funakoshi M, Funakoshi M, Gold R, Goldin A L, Hinck D, Hinck D, Hofer D, Kocsis P, Kocsis P, Kornelia Tekes, Lipták J, Luo Z, Melka A, Novales-Li P, Novales-Li P, Nádor K, Okada H, Ono H, Patel KS, Prabhoo R, Pratzel HG, Pórszász J, Quasthoff S, Quasthoff S, Rao R, Sakaue A, Sakitama K, Sakitama K, Stamenova P, Svensson P, Vora A, Zhao F   +36 more
core   +3 more sources

Laryngeal mask airway without muscle relaxant in femoral head replacement in elderly patients

Experimental and Therapeutic Medicine, 2015
The number of elderly patients undergoing femoral head replacement surgeries is on the increase. These patients often suffer from comorbidity such as cardiovascular and cerebrovascular complications, which limits the ability of medical teams to employ ...
Ming Kong, Beiping Li, Yun-Ping Tian
openalex   +3 more sources