In Vivo Anti-Inflammatory, Analgesic, Muscle Relaxant, and Sedative Activities of Extracts from Syzygium cumini (L.) Skeels in Mice [PDF]
Evid Based Complement Alternat Med, 2022 In the current study, the folklore medicine, Syzygium cumini, was experimentally evaluated for anti-inflammatory, analgesic, sedative, and muscle relaxant effects. The extract and fractions of S. cumini were found safe up to 1000 mg/kg with no mortality,
A. Rauf +8 more
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Long-Term Use of Muscle Relaxant Medications for Chronic Pain
JAMA Netw OpenKey Points Question What are the effectiveness and safety of long-term use of muscle relaxant medications for the treatment of chronic pain? Findings In this systematic review of 44 studies including 2482 participants, 9 unique muscle relaxant ...
Benjamin J. Oldfield +6 more
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In-vitro antioxidant, lipoxygenase inhibitory, and in-vivo muscle relaxant potential of the extract and constituent isolated from Diospyros kaki (Japanese Persimmon) [PDF]
Heliyon, 2023 Diospyros kaki (Japanese persimmon) is cultivated specious of the Diospyros genus. D. kaki is a multi-medicinal application in the folk system for the cure of ischemic stroke, angina, atherosclerosis, muscle relaxation, internal hemorrhage, hypertension,
Adil Mujawah +5 more
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In Vivo Antinociceptive, Muscle Relaxant, Sedative, and Molecular Docking Studies of Peshawaraquinone Isolated from Fernandoa adenophylla (Wall. ex G. Don) Steenis [PDF]
ACS Omega, 2021 Fernandoa adenophylla (Wall. ex G. Don) Steenis is traditionally used to cure various diseases and can be included as an ingredient in massage oils, which are supposed to comfort muscular tension and pain.
F. Alhumaydhi +7 more
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Muscle relaxant and antipyretic effects of pentacyclic triterpenes isolated from the roots of Diospyros lotus L [PDF]
HeliyonThe present article describes the muscle relaxant and antipyretic effects of pentacyclic triterpenes, oleanolic acid (OA), ursolic acid (UA) and betulinic acid (BA) isolated from roots of Diospyros lotus in animal models.
Ajmal Khan +10 more
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Molecular mechanism of BK channel activation by the smooth muscle relaxant NS11021 [PDF]
J Gen Physiol, 2020 Large-conductance Ca2+-activated K+ channels (BK channels) are key drug targets due to their association with a wide variety of neurological disorders. Rockman et al.
M. Rockman +2 more
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An assessment of the centrally acting muscle relaxant tolperisone on driving ability and cognitive effects compared to placebo and cyclobenzaprine [PDF]
J Clin Pharm Ther, 2020 Tolperisone is a centrally acting muscle relaxant under development in the United States as a treatment for acute and painful symptoms of muscle spasms. The objective of this three‐way, randomized, blinded, three‐period crossover study was to assess the ...
J. Caron +4 more
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Comparison of laryngeal mask airway (LMA) insertion with and without muscle relaxant in pediatric anesthesia; a randomized clinical trial [PDF]
Heliyon, 2022 Introduction: This study aimed to evaluate the effectiveness of using muscle relaxant on the ease of laryngeal mask airway (LMA) insertion and possibility of its related complications.
Ziae Totonchi +4 more
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Journal of Traditional and Complementary Medicine, 2018 Valeriana officinalis L. root extracts are traditionally taken for their sedative and anxiolytic properties and are also used for muscle relaxation. Relaxant effects were clearly observed on smooth muscle whereas data on effects on skeletal muscle are ...
Dorian Caudal +7 more
doaj +2 more sources
An ambulatory dental treatment of a child with Rett syndrome and limited mouth opening under muscle relaxant-free general anesthesia: a case report [PDF]
BMC AnesthesiologyBackground Rett Syndrome (RTT) is a rare, severe, and progressive developmental disorder with intellectual disability. Anesthesia in RTT patients presents a range of challenges.
Xiao Tan +3 more
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