Pepducins as a potential treatment strategy for asthma and COPD. [PDF]
, 2018 Current therapies to treat asthma and other airway diseases primarily include anti-inflammatory agents and bronchodilators. Anti-inflammatory agents target trafficking and resident immunocytes and structural cells, while bronchodilators act to prevent or
Benovic, Jeffrey L. +4 more
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Synthesis and Structure-Activity Relationships of Pyridoxal-6-arylazo-5'-phosphate and Phosphonate Derivatives as P2 Receptor Antagonists. [PDF]
, 1998 Novel analogs of the P2 receptor antagonist pyridoxal-5'-phosphate-6-phenylazo-2',4'-disulfonate (PPADS) were synthesized. Modifications were made through functional group substitution on the sulfophenyl ring and at the phosphate moiety through the ...
Boyer, José L. +13 more
core +3 more sources
The Vasorelaxant Effect of p-Cymene in Rat Aorta Involves Potassium Channels
The Scientific World Journal, 2015 The monoterpenes are the main constituents of most essential oils and p-cymene is a monoterpene commonly found in various species of aromatic herbs, which has been reported for anti-inflammatory, antinociceptive, and antimicrobial activities.
Martapolyana T. M. Silva +8 more
doaj +1 more source
The Relaxant Effect of Plantago Major on Rat Tracheal Smooth Muscles and Its Possible Mechanisms
Iranian Journal of Allergy, Asthma and Immunology, 2020 This study was conducted to evaluate the possible mechanisms of the relaxant effects of hydroalcoholic extract of Plantago major (P. major) on tracheal smooth muscle (TSM) in rats. The effects of cumulative concentrations of P. major (5, 10, 20 and 40 mg/
Javad Boskabadi +2 more
doaj +1 more source
Self-Assistant: Portable Progressive Muscle Relaxation Training Interface for Anxiety Reduction in Office Workers [PDF]
arXiv, 2023 Workload often triggers anxiety for office workers. While a variety of stress intervention and management techniques have been explored, there exist only a few of portable tangible interfaces for anxiety reduction. Contributing to the body of work, we introduce Self-Assistant, a portable anxiety intervention training interface.
arxiv
Sugammadex for reversal of neuromuscular blockade: A retrospective analysis of clinical outcomes and cost-effectiveness in a single center [PDF]
, 2016 OBJECTIVE: The aim of the study is to evaluate the clinical and economic impact of introducing a rocuronium-neostigmine-sugammadex strategy into a cisatracurium-neostigmine regimen for neuromuscular block (NMB) management.
BARATTO, FABIO +3 more
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Zdravniški Vestnik, 2018 We present our position statement for the use of sugammadex, a specific binder for aminosteroid muscle relaxants, in the most common clinical circumstances (in the case of an emergency intubation, when the patient cannot be ventilated or intubated; in ...
Neva Požar Lukanović +7 more
doaj +1 more source
Simultaneous Modeling of In Vivo and In Vitro Effects of Nondepolarizing Neuromuscular Blocking Drugs [PDF]
arXiv, 2023 Nondepolarizing neuromuscular blocking drugs (NDNBs) are clinically used to produce muscle relaxation during general anesthesia. This paper explores a suitable model structure to simultaneously describe in vivo and in vitro effects of three clinically used NDNBs, cisatracurium, vecuronium, and rocuronium. In particular, it is discussed how to reconcile
arxiv
The Differences in the Relaxant Effects of Different Fractions of Rosa damascena on Guinea Pig Tracheal Smooth Muscle [PDF]
Iranian Journal of Basic Medical Sciences, 2010 Objective(s)In the present study, the differences in the relaxant effects of aqueous, ethyl acetate and n-butanol fractions of Rosa damascena on tracheal smooth muscle of guinea pigs were examined.
Hassan Rakhshandah +4 more
doaj
Multi-objective genetic optimisation for self-organising fuzzy logic control [PDF]
, 1998 This is the post-print version of the article. The official published version can be accessed from the link below.A multi-objective genetic algorithm is developed for the purpose of optimizing the rule-base of a Self-Organising Fuzzy Logic Control ...
Abbod, MF, Linkens, DA, Mahfouf, M
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