Results 71 to 80 of about 1,552,624 (372)

Sedative effects of detomidine and midazolam combination in horses

open access: yesOpen Veterinary Journal
Background: The combination of detomidine and midazolam may provide safer sedation with muscle-relaxant effects, which is particularly necessary during standing procedures. Aim: Thus, the objective of this study was to evaluate the sedative and muscle-
Érika Ribeiro Gomes   +9 more
doaj   +1 more source

Development and Evaluation of Nanoemulsion Loaded Metaxalone for the Treatment of Pain and Injury

open access: yesEngineering Proceedings, 2023
Spasticity is a disorder characterized by an unnatural rise in muscular tone or stiffness, which may impair speech or movement and be accompanied by discomfort or pain.
Shivani S. Pawar   +2 more
doaj   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

Characterization of the vagal motor neurons projecting to the guinea pig airways and esophagus

open access: yesFrontiers in Neurology, 2010
Distinct parasympathetic postganglionic neurons mediate contractions and relaxations of the guinea pig airways. We set out to characterize the vagal inputs that regulate contractile and relaxant airway parasympathetic postganglionic neurons. Single and
Alice eMcGovern, Stuart eMazzone
doaj   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou   +4 more
wiley   +1 more source

Diabetes potentiates acetylcholine-induced relaxation in rabbit renal arteries [PDF]

open access: yes, 2001
The response of rabbit renal arteries to acetylcholine and its endothelial modulation in diabetes were investigated. Acetylcholine induced concentration-related endothelium-dependent relaxation of renal arteries that was significantly more potent in ...
Alabadí Ferrer, José Antonio   +5 more
core   +2 more sources

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

open access: yesAdvanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt   +2 more
wiley   +1 more source

A Randomized controlled trial on the effectiveness of ultrasound therapy with muscle relaxant gel versus aquasonic transmission gel combined with strengthening exercises protocol in treating text neck syndrome

open access: yesФізична реабілітація та рекреаційно-оздоровчі технології
Purpose. The term "text neck" refers to an overuse or repetitive stress injury condition where a person is stooped down for extended periods of time at their phone or other electronic devices with their head drooping or flexed forward. The study aimed to
Boopathy D.   +4 more
doaj   +1 more source

Magnesium sulfate enhances non-depolarizing muscle relaxant vecuronium action at adult muscle-type nicotinic acetylcholine receptor in vitro

open access: yesActa Pharmacologica Sinica, 2011
Aim:To investigate the effect of magnesium sulfate and its interaction with the non-depolarizing muscle relaxant vecuronium at adult muscle-type acetylcholine receptors in vitro.Methods:Adult muscle-type acetylcholine receptors were expressed in HEK293 ...
Hong Wang   +6 more
semanticscholar   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

open access: yesAdvanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim   +4 more
wiley   +1 more source

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