Results 231 to 240 of about 105,201 (288)
Some of the next articles are maybe not open access.
Effects of tizanidine, a centrally acting muscle relaxant, on motor systems
General Pharmacology: The Vascular System, 1986Effects of tizanidine were studied with special reference to the effect on motor systems. The drug effectively reduced the intercollicular decerebrate rigidity and gamma-activity indirectly recorded from muscle spindle afferent discharges without showing the direct inhibitory effect on muscle spindles in rats.
H, Ono +8 more
openaire +2 more sources
Biofeedback and Self-Regulation, 1980
The relationship of "awareness of muscle tension" to depth of relaxation was explored. In one experiment, accuracy of forearm flexor control was assessed using the psychophysical method of magnitude production, and depth of flexor relaxation was measured using the integrated EMG before and after EMG biofeedback training.
D W, Stilson, I, Matus, G, Ball
openaire +2 more sources
The relationship of "awareness of muscle tension" to depth of relaxation was explored. In one experiment, accuracy of forearm flexor control was assessed using the psychophysical method of magnitude production, and depth of flexor relaxation was measured using the integrated EMG before and after EMG biofeedback training.
D W, Stilson, I, Matus, G, Ball
openaire +2 more sources
A search for more effective muscle relaxants among the glycerol ethers and dioxolanes.
Journal of Pharmacology and Experimental Therapeutics, 19541) Centrally acting muscle relaxants of mephenesin type are shown to abolish pinna reflex earlier than corneal reflex, in contrast to many other types of central depressants.
J. Goodsell +3 more
semanticscholar +1 more source
Glyceryl Guaiacolate: a Centrally Acting Muscle Relaxant
Equine Veterinary Journal, 1970Summary A review of the history of centrally‐acting muscle relaxants has been given. The centrally‐acting muscle relaxant glyceryl guaiacolate has been used extensively in continental Europe and, within recent years, has attracted the attention of North American workers.
openaire +1 more source
Effects of NK433, a new centrally acting muscle relaxant, on masticatory muscle reflexes in rats
European Journal of Pharmacology, 1996The effects of (-)-(R)-2-methyl-3-(1-pyrrolidinyl)-4'- trifluoromethylpropiophenone monohydrochloride (NK433), a novel centrally acting muscle relaxant, on masticatory muscle reflexes were investigated in rats. NK433 inhibited the monosynaptic tonic vibration reflex of the masseter muscle and the polysynaptic tonic periodontal masseteric reflex.
Y, Ozawa +3 more
openaire +2 more sources
Pharmacological associations of Central Serous Chorioretinopathy: Looking beyond corticosteroids.
Survey of ophthalmologyCentral serous chorioretinopathy (CSCR) has multiple associations and risk factors. Of these, psychological stress, corticosteroid treatment, and specific personality traits are well recognized.
Manish Jain +3 more
semanticscholar +1 more source
Involvement of imidazoline receptors in the centrally acting muscle-relaxant effects of tizanidine
European Journal of Pharmacology, 2002The centrally acting muscle relaxant tizanidine has an imidazoline structure and binds not only to alpha(2)-adrenoceptors but also to imidazoline receptors. The role of imidazoline receptors in the muscle-relaxant effect of tizanidine was studied using the alpha(2)-adrenoceptor/imidazoline receptor antagonist idazoxan and the alpha(2)-adrenoceptor ...
Motoko, Honda +3 more
openaire +2 more sources
[Cleavage and biotransformation of the central muscle relaxant chlormezanone].
Die Pharmazie, 1998Chlormezanone, a chiral centrally acting muscle relaxant, will be cleaved at its S-C-1 bond by an autoprotolytic process. The optimum of chemical stability exists between pH 2 up to pH 9 with a maximum at pH 7.4. The plasma half life at 37 degrees C is 76 h.
H, Oelschläger +8 more
openaire +1 more source
Cyclobenzaprine, a centrally acting muscle relaxant, acts on descending serotonergic systems
European Journal of Pharmacology, 1996The centrally acting muscle relaxant cyclobenzaprine was thought to be an alpha 2-adrenoceptor agonist that reduced muscle tone by decreasing the activity of descending noradrenergic neurons. In the present study, we examined the effects of cyclobenzaprine on descending neurons by measuring the monosynaptic reflex in rats.
H, Kobayashi, Y, Hasegawa, H, Ono
openaire +2 more sources
Effects of centrally acting muscle relaxants on post-rotatory nystagmus in the rabbit
General Pharmacology: The Vascular System, 19891. The effects of some centrally acting muscle relaxants on the post-rotatory nystagmus induced by rotatory stimulation were investigated in the rabbit, to examine the action of the drugs on vestibular function. 2. Tolperisone-HCl (5-10 mg/kg, i.v.) and baclofen (1-3 mg/kg, i.v.) decreased the number of post-rotatory nystagmus beats dose-dependently ...
M, Ishikawa +3 more
openaire +2 more sources