Results 51 to 60 of about 18,960 (304)

Use of Fixed Dose Combination (FDC) Drugs in India: Central Regulatory Approval and Sales of FDCs Containing Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Metformin, or Psychotropic Drugs. [PDF]

, 2015
In 2012, an Indian parliamentary committee reported that manufacturing licenses for large numbers of fixed dose combination (FDC) drugs had been issued by state authorities without prior approval of the Central Drugs Standard Control Organization (CDSCO)
Kadam, A, Mahajan, R, McGettigan, P, Pollock, AM, Roderick, P   +4 more
core   +5 more sources

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Our Experience of Managing Central Airway Tumors: Anesthesia Perspectives

Annals of Cardiac Anaesthesia
Adult patients with central airway tumors commonly present with dyspnea on exertion. These patients may remain asymptomatic until more than half of the airway diameter is obliterated.
Thushara Madathil, Devika Poduval, Tony Jose, Nagarjuna Panidapu, Don Jose, Tinku Joseph, Praveen Kumar Neema   +6 more
doaj   +1 more source

Central muscle relaxant activities of 2-methyl-3-aminopropiophenone derivatives.

Folia Pharmacologica Japonica, 1987
In this experiment, we synthetized new 2-methyl-3-aminopropiophenone (MP) derivatives, whose structure is known to have central muscle relaxant activities, and quinolizidine and indan . tetralin derivatives derived from MP by cyclization, and we investigated the central muscle relaxant activity.
H, Kontani, A, Mano, R, Koshiura, M, Yamazaki, Y, Shimada, M, Oshita, K, Morikawa, H, Kato, Y, Ito   +8 more
openaire   +3 more sources

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

The neuropeptide transcriptome of a model echinoderm, the sea urchin Strongylocentrotus purpuratus [PDF]

, 2012
The work reported here was supported by a grant from the University of London Central Research ...
Elphick, MR, Rowe, ML
core   +1 more source

Charge‐Induced Morphing Gels for Bioinspired Actuation

Advanced Functional Materials, EarlyView.
This study introduces a novel electroactive actuation mechanism that enables the gel material to generate substantial and reversible shape‐changing while preserving topological and isochoric (volumetric) equivalence. The resultant morphing behaviors can mimic the movements of muscle‐driven organelles in nature, including cilia‐like beating and ...
Ciqun Xu, Saba Firouznia, Charl F. J. Faul, Majid Taghavi, Jonathan Rossiter   +4 more
wiley   +1 more source

Perspectives on next steps in classification of oro-facial pain - Part 3: biomarkers of chronic oro-facial pain - from research to clinic [PDF]

, 2015
The purpose of this study was to review the current status of biomarkers used in oro-facial pain conditions. Specifically, we critically appraise their relative strengths and weaknesses for assessing mechanisms associated with the oro-facial pain ...
Alnaas, D, Cairns, B E, Ceusters, W, Michelotti, A, Nasri-Heir, C, Ohrbach, R   +5 more
core   +1 more source

Electroactive Liquid Crystal Elastomers as Soft Actuators

Advanced Functional Materials, EarlyView.
Electroactive liquid crystal elastomers (eLCEs) can be actuated via electromechanical, electrochemical, or electrothermal effects. a) Electromechanical effects include Maxwell stress, electrostriction, and the electroclinic effect. b) Electrochemical effects arise from electrode redox reactions.
Yakui Deng, Min‐Hui Li
wiley   +1 more source

Profile of drugs used for self-medication by elderly attended at a referral center

Einstein (São Paulo)
Objective To determine the profile of medications used for self-medication by the elderly. Methods A cross-sectional study based on interviews with elderly seen at a reference center for Elderly Health of a teaching hospital, from July 2014 to July ...
Samanta Bárbara Vieira de Oliveira, Soraya Coelho Costa Barroso, Maria Aparecida Camargos Bicalho, Adriano Max Moreira Reis   +3 more
doaj   +1 more source