Results 11 to 20 of about 18,977 (204)

The Dosage of Muscle Relaxants in Morbidly Obese Patients in Daily Practice – A Narrative Review [PDF]

International Journal of General Medicine
Paweł Radkowski, Maria Derkaczew, Dariusz Onichimowski   +2 more
exaly   +2 more sources

Estimation of the effect-site equilibration rate constant using the time-to-peak effect of muscle relaxants measured by train-of-four stimulation during general anesthesia induction [PDF]

Korean Journal of Anesthesiology, 2018
Background The concept of the effect-site concentration of anesthetic agents is important. The effect compartment model can be explained using the concepts of effect-site concentration and effect-site equilibration rate constant (ke0).
Se Yeon Park, Hyun Jung Kim, Yun Suk Choi, So-hui Yun, Jong Cook Park   +4 more
doaj   +1 more source

Anaesthetic Management of a Patient with Myasthenia Gravis for Laparascopic Cholecystectomy: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2019
Myasthenia gravis is an autoimmune disease, which presents as fatigue and muscle weakness due to destruction of nicotinic receptors. Perioperative management of such patients is challenging due to altered pharmacology of drugs especially muscle relaxants
Jaya Choudhary, Aaditya Prabhudesai, Anshika Agarwal   +2 more
doaj   +1 more source

Receptor subunit compositions underly distinct potencies of a muscle relaxant in fast and slow muscle fibers

Frontiers in Physiology, 2022
A line of studies in the 1960s–1980s suggested that muscle relaxants do not work uniformly on all skeletal muscles, though its mechanism has not been clarified.
Manami Yamashita, Yoshihiro Egashira, Shuntaro Nakamura, Souhei Sakata, Fumihito Ono   +4 more
doaj   +1 more source

Muscle relaxant use and the associated risk of incident frailty in patients with diabetic kidney disease: a longitudinal cohort study

Therapeutic Advances in Drug Safety, 2021
Background: Patients with diabetic kidney disease (DKD) are at an increased risk of frailty. The exposure to muscle relaxants frequently leads to adverse effects despite their modest therapeutic efficacy, but whether muscle relaxants predispose users to ...
Szu-Ying Lee, Jui Wang, Hung-Bin Tsai, Chia-Ter Chao, Kuo-Liong Chien, Jenq-Wen Huang   +5 more
doaj   +1 more source

Sedation, Analgesia, and Muscle Relaxation During VV-ECMO Therapy in Patients With Severe Acute Respiratory Syndrome Coronavirus Type 2 (SARS-CoV-2): A Single-Center, Retrospective, Observational Study

Frontiers in Medicine, 2021
Objective: The pharmacokinetics and pharmacodynamics of ECMO-supported sedative, analgesic, and muscle relaxants have changed, but there are insufficient data to determine the optimal dosing strategies for these agents.
Fang Wu, Mingna Li, Zhongwei Zhang, Jiawei Shang, Yong Guo, Yingchuan Li   +5 more
doaj   +1 more source

Central muscle relaxants in rheumatology practice

Современная ревматология, 2021
The article describes the general principles of the treatment of musculoskeletal pain, discusses modern approaches to the treatment of osteoarthritis (OA) and nonspecific back pain (NBS).
E. Yu. Polishchuk, A. S. Potapova, A. E. Karateev   +2 more
doaj   +1 more source

Cholinergic Chemotransmission and Anesthetic Drug Effects at the Carotid Bodies

Molecules, 2020
General anesthesia is obtained by administration of potent hypnotics, analgesics and muscle relaxants. Apart from their intended effects (loss of consciousness, pain relief and muscle relaxation), these agents profoundly affect the control of breathing ...
Maarten Honing, Chris Martini, Monique van Velzen, Marieke Niesters, Albert Dahan, Martijn Boon   +5 more
doaj   +1 more source

Intraoperative Monitoring of Neuromuscular Blockade

Life, 2023
There is a global trend of new guidelines highly recommending quantitative neuromuscular monitoring in the operating room. In fact, it is almost certain that quantitatively monitoring the depth of intraoperative muscle paralysis may permit the rational ...
Cyrus Motamed
doaj   +1 more source

Muscle relaxants as alternative analgesics in the treatment of nonspecific back pain

Неврология, нейропсихиатрия, психосоматика, 2017
Only 50% of patients treated for back pain achieve effective relief. This is to some extent due to physicians' insufficient knowledge about the therapeutic strategies recommended in most expert guidelines.
G. R. Tabeeva
doaj   +1 more source