Results 21 to 30 of about 1,511,212 (387)

Receptor subunit compositions underly distinct potencies of a muscle relaxant in fast and slow muscle fibers

open access: yesFrontiers in Physiology, 2022
A line of studies in the 1960s–1980s suggested that muscle relaxants do not work uniformly on all skeletal muscles, though its mechanism has not been clarified.
Manami Yamashita   +4 more
doaj   +1 more source

Muscle relaxant use and the associated risk of incident frailty in patients with diabetic kidney disease: a longitudinal cohort study

open access: yesTherapeutic Advances in Drug Safety, 2021
Background: Patients with diabetic kidney disease (DKD) are at an increased risk of frailty. The exposure to muscle relaxants frequently leads to adverse effects despite their modest therapeutic efficacy, but whether muscle relaxants predispose users to ...
Szu-Ying Lee   +5 more
doaj   +1 more source

Sedation, Analgesia, and Muscle Relaxation During VV-ECMO Therapy in Patients With Severe Acute Respiratory Syndrome Coronavirus Type 2 (SARS-CoV-2): A Single-Center, Retrospective, Observational Study

open access: yesFrontiers in Medicine, 2021
Objective: The pharmacokinetics and pharmacodynamics of ECMO-supported sedative, analgesic, and muscle relaxants have changed, but there are insufficient data to determine the optimal dosing strategies for these agents.
Fang Wu   +5 more
doaj   +1 more source

Pharmacodynamic interactions between muscle relaxants and other medications in practice of anesthesia [PDF]

open access: yesFarmacja Polska, 2023
Knowledge of drug interactions is an essential element of medical practice. Along with the increasing occurrence of multimorbidity and the associated multi-drug use, the number of possible combinations of preparations is constantly rising.
Paweł Radkowski, Rafał Marek Okoński
doaj   +1 more source

Cholinergic Chemotransmission and Anesthetic Drug Effects at the Carotid Bodies

open access: yesMolecules, 2020
General anesthesia is obtained by administration of potent hypnotics, analgesics and muscle relaxants. Apart from their intended effects (loss of consciousness, pain relief and muscle relaxation), these agents profoundly affect the control of breathing ...
Maarten Honing   +5 more
doaj   +1 more source

Intraoperative Monitoring of Neuromuscular Blockade

open access: yesLife, 2023
There is a global trend of new guidelines highly recommending quantitative neuromuscular monitoring in the operating room. In fact, it is almost certain that quantitatively monitoring the depth of intraoperative muscle paralysis may permit the rational ...
Cyrus Motamed
doaj   +1 more source

Muscle weakness after muscle relaxants: An audit of clinical practice [PDF]

open access: yes, 2004
Publisher's copy made available with the permission of the publisher © Australian Society of AnaesthetistsResidual muscle weakness after general anaesthesia, assessed using handgrip strength, was audited in a teaching hospital.
Alkhazrajy, W.   +2 more
core   +1 more source

Muscle relaxants as alternative analgesics in the treatment of nonspecific back pain

open access: yesНеврология, нейропсихиатрия, психосоматика, 2017
Only 50% of patients treated for back pain achieve effective relief. This is to some extent due to physicians' insufficient knowledge about the therapeutic strategies recommended in most expert guidelines.
G. R. Tabeeva
doaj   +1 more source

Central muscle relaxants in rheumatology practice

open access: yesСовременная ревматология, 2021
The article describes the general principles of the treatment of musculoskeletal pain, discusses modern approaches to the treatment of osteoarthritis (OA) and nonspecific back pain (NBS).
E. Yu. Polishchuk   +2 more
doaj   +1 more source

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