Results 171 to 180 of about 8,631,981 (422)

Handling rescue therapy in myasthenia gravis clinical trials: why it matters and why you should care

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Myasthenia gravis (MG) clinical trials typically allow rescue therapy during follow‐up in the event of marked worsening of MG symptoms. Failure to appropriately address rescue therapy in defining treatment effects and planning statistical analyses may yield biased estimates, increase false positive rates, or decrease statistical power – all of
Justin M. Leach, Inmaculada Aban, Gary Cutter, Michael Benatar   +3 more
wiley   +1 more source

Maximizing Consistent Force Output for Shape Memory Alloy Artificial Muscles in Soft Robots [PDF]

arXiv
Soft robots have immense potential given their inherent safety and adaptability, but challenges in soft actuator forces and design constraints have limited scaling up soft robots to larger sizes. Electrothermal shape memory alloy (SMA) artificial muscles have the potential to create these large forces and high displacements, but consistently using ...
arxiv  

Grip and muscle strength dynamometry in acute burn injury: Evaluation of an updated assessment protocol [PDF]

, 2018
External stabilization is reported to improve reliability of hand held dynamometry, yet this has not been tested in burns. We aimed to assess the reliability of dynamometry using an external system of stabilization in people with moderate burn injury and
Edgar, Dale W, Gittings, Paul M, Hince, Dana A, Wand, Benedict M, Wood, Fiona M   +4 more
core   +1 more source

UDP‐glucose dehydrogenase variants cause dystroglycanopathy

Annals of Clinical and Translational Neurology, EarlyView.
Abstract UDP‐glucose dehydrogenase (UGDH) variants have been associated with hypotonia, developmental delay, and epilepsy. We report the first pathologic evidence of dystroglycanopathy in siblings with UGDH variants. Both presented around 6 months with developmental delay and elevated creatinine kinase.
Anna M. Reelfs, Carrie M. Stephan, Theresa M. Czech, Mary O. Cox, Soumya Joseph, Benjamin W. Darbro, Steven A. Moore, Kevin P. Campbell, Katherine D. Mathews   +8 more
wiley   +1 more source

FEEDLOT PERFORMANCE, CARCASS COMPOSITION AND EFFICIENCY OF MUSCLE GAIN IN BULLS AND STEERS OF DIFFERENT MATURE SIZE SLAUGHTERED AT SIMILAR LEVELS OF FATNESS [PDF]

, 1984
S. D. M. Jones, T. D. Burgess, J. W. Wilton, C. H. WATSON   +3 more
openalex   +1 more source

Muscle fibre typing, collagen composition analysis of breast and thigh meats in two breeds of chicken of different growth performance [PDF]

, 2010
The present study was done to evaluate the type of muscle fibre composition in thigh and breast muscle of Red Jungle fowl and Ross. It was also to evaluate the collagen composition in thigh and breast muscle of Red Jungle fowl and Ross.
Abu Bakar @ Zakaria, Md Zuki, Lee, Siang Pin   +1 more
core  

Progressive Myoclonus Epilepsy: Distinctive MRI Changes in Cerebellar and Motor Networks

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive myoclonus epilepsy (PME) is a rare generalized epilepsy syndrome with a well‐characterized genetic basis. The brain networks that are affected to give rise to the distinctive symptoms of PME are less well understood. Methods Eleven individuals with PME with a confirmed genetic diagnosis and 22 controls were studied.
Jillian M. Cameron, Remika Mito, Samuel F. Berkovic, Graeme D. Jackson   +3 more
wiley   +1 more source

DIFFERENTIAL EFFECTS OF THE CALCIUM ANTAGONIST, VERAPAMIL, ON LUMEN SIZES OF TERMINAL ARTERIOLES AND MUSCULAR VENULES IN THE RAT MESENTERIC, PIAL AND SKELETAL MUSCLE MICROVASCULATURES [PDF]

, 1980
Burton M. Altura, Bella T. Altura, Asefa Gebrewold   +2 more
openalex   +1 more source

Cerebello‐Prefrontal Connectivity Underlying Cognitive Dysfunction in Spinocerebellar Ataxia Type 2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 2 (SCA2) is a hereditary cerebellar degenerative disorder, with motor and cognitive symptoms. The constellation of cognitive symptoms due to cerebellar degeneration is named cerebellar cognitive affective syndrome (CCAS), which has increasingly been recognized to profoundly impact patients' quality of life;
Ami Kumar, Ruo‐Yah Lai, Zena Fadel, Yicheng Lin, Pia Parekh, Rachel Griep, Ming‐Kai Pan, Sheng‐Han Kuo   +7 more
wiley   +1 more source

Longitudinal trajectories of muscle impairments in growing boys with Duchenne muscular dystrophy.

PLoS ONE
BackgroundInsights into the progression of muscle impairments in growing boys with Duchenne muscular dystrophy (DMD) remain incomplete due to the frequent oversight of normal maturation as a confounding factor, thereby restricting the delineation of sole
Ines Vandekerckhove, Marleen Van den Hauwe, Tijl Dewit, Geert Molenberghs, Nathalie Goemans, Liesbeth De Waele, Anja Van Campenhout, Friedl De Groote, Kaat Desloovere   +8 more
doaj   +1 more source