Spontaneous physical activity down-regulates Pax7 in cancer cachexia [PDF]
Emerging evidence suggests that the muscle microenvironment plays a prominent role in cancer cachexia. We recently showed that NF-kB - induced Pax7 overexpression impairs the myogenic potential of muscle precursors in cachectic mice, suggesting that ...
Adamo, Sergio+7 more
core +5 more sources
Interactive Modelling of Volumetric Musculoskeletal Anatomy [PDF]
We present a new approach for modelling musculoskeletal anatomy. Unlike previous methods, we do not model individual muscle shapes as geometric primitives (polygonal meshes, NURBS etc.). Instead, we adopt a volumetric segmentation approach where every point in our volume is assigned to a muscle, fat, or bone tissue.
arxiv +1 more source
Using a Conformal Water Bolus to Adjust Heating Patterns of Microwave Waveguide Applicators [PDF]
Background: Hyperthermia, i.e., raising tissue temperature to 40-45°C for 60 min, has been demonstrated to increase the effectiveness of radiation and chemotherapy for cancer.
Dewhirst+9 more
core +2 more sources
Skeletal Muscle Fiber Size and Capillarity
SummaryThe ATPase technique following preincubation in an acid medium (pH 3.8–4.0) was used to visualize capillaries. After preincubation at a pH of 4.5, in combination with the DPNH tetrazolium reductase, it was used to identify fiber types. A positive correlation has been demonstrated between fiber cross sectional area and C:F, indicating that large ...
Natalio Banchero, A. H. Sillau
openaire +3 more sources
Skeletal muscle contributions to reduced fitness in cystic fibrosis youth
BackgroundIncreased maximal oxygen uptake (V̇O2max) is beneficial in children with cystic fibrosis (CF) but remains lower compared to healthy peers.
Owen William Tomlinson+9 more
doaj +1 more source
Muscle contraction and the elasticity-mediated crosstalk effect [PDF]
Cooperative action of molecular motors is essential for many cellular processes. One possible regulator of motor coordination is the elasticity-mediated crosstalk (EMC) coupling between myosin II motors whose origin is the tensile stress that they collectively generate in actin filaments.
arxiv +1 more source
The effects of hibernation on the contractile and biochemical properties of skeletal muscles in the thirteen-lined ground squirrel, Ictidomys tridecemlineatus [PDF]
Hibernation is a crucial strategy of winter survival used by many mammals. During hibernation, thirteen-lined ground squirrels, Ictidomys tridecemlineatus, cycle through a series of torpor bouts, each lasting more than a week, during which the animals ...
Allan+45 more
core +2 more sources
Resistance training is often recommended for combined increases in traditional and alternative hamstrings-to-quadriceps (H:Q) ratios in order to reduce knee strength imbalance and associated hamstrings and knee ligament injury risk. The aim of this study
Cassio V. Ruas+4 more
doaj +1 more source
Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network [PDF]
Long non-coding RNAs (lncRNAs) are emerging as important players in the regulation of several aspects of cellular biology. For a better comprehension of their function, it is fundamental to determine their tissue or cell specificity and to identify their
Alessio, Enrico+13 more
core +1 more source
Forearm Flexor Muscles in Children with Cerebral Palsy Are Weak, Thin and Stiff
Children with cerebral palsy (CP) often develop reduced passive range of motion with age. The determining factor underlying this process is believed to be progressive development of contracture in skeletal muscle that likely changes the biomechanics of ...
Eva Pontén+9 more
doaj +1 more source