Clinical and Experimental Neuroimmunology, EarlyView.Abstract Objective To evaluate the responsiveness of T cells from newly diagnosed multiple sclerosis (MS) patients to CD46 co‐stimulation, a membrane co‐factor protein potentially involved in MS pathogenesis. Methods T cells from MS patients and non‐diseased symptomatic controls (SC) were activated in vitro with or without αCD46 antibody co‐stimulation.
Linda Sundvall +6 more
wiley +1 more source
Scientific ReportsPrevious studies have reported the effects of vibratory stimulation (VS) therapy in reducing upper extremity spasticity after stroke. However, the effective location of the VS in patients with stroke remains unclear.
Kenta Takeuchi +4 more
doaj +1 more source
THE STIFFNESS OF SPASTIC MUSCLE [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1961 openaire +3 more sources
Anatomical locations of the motor endplates of sartorius muscle for botulinum toxin injections in treatment of muscle spasticity. [PDF]
Surg Radiol Anat, 2021 Yi KH +5 more
europepmc +1 more source
Rediscovery of the Tubulin β‐4A p.Arg2Gly Variant in Whispering Dysphonia: A Report from Austria
Movement Disorders, EarlyView.
Omar Keritam +7 more
wiley +1 more source
Expanding the Phenotypic Spectrum of SPG7 Rare Damaging Variants: Insights From a Hungarian Cohort
Clinical Genetics, EarlyView.Rare damaging SPG7 variants were detected in 58 patients with spastic paraplegia, ataxia, mitochondrial dysfunction, or motoneuron lesions. The cumulative prevalence of SPG7‐related conditions in Hungary was estimated. Phenotypic spectra and mitochondrial dysfunction were assessed in monoallelic and biallelic cases, contributing to the understanding of
Idris Janos Jimoh +10 more
wiley +1 more source
Botulinum toxin injection for Cockayne syndrome with muscle spasticity over bilateral lower limbs: A case report. [PDF]
World J Clin Cases, 2021 Hsu LC +7 more
europepmc +1 more source
The Natural Course of Bosch‐Boonstra‐Schaaf Optic Atrophy Syndrome
Clinical Genetics, EarlyView.Here, we present data on genetic variants and phenotype development of 47 individuals with Bosch‐Boonstra‐Schaaf optic atrophy syndrome, a rare neurodevelopmental disorder, highlighting the fact that the disease does not appear to be fundamentally progressive.
Ilia Valentin +4 more
wiley +1 more source
Localization of nerve entry points and the center of intramuscular nerve-dense regions in the adult pectoralis major and pectoralis minor and its significance in blocking muscle spasticity. [PDF]
J Anat, 2021 Li Y, Wang M, Tang S, Zhu X, Yang S.
europepmc +1 more source
Clinical Genetics, EarlyView.Cerebrotendinous xanthomatosis is due to biallelic pathogenic variants in CYP27A1. We report a new patient and his good neurocognitive outcome on the chenodeoxycholic acid treatment despite therapy starting at the age of 34 years. This highlights the importance of recognizing treatable inherited metabolic diseases at any age.
Randa Sultan +6 more
wiley +1 more source