Results 141 to 150 of about 1,566,168 (324)

Transcutaneous spinal cord stimulation neuromodulates pre- and postsynaptic inhibition in the control of spinal spasticity

open access: yesCell Reports Medicine
Summary: Aside from enabling voluntary control over paralyzed muscles, a key effect of spinal cord stimulation is the alleviation of spasticity. Dysfunction of spinal inhibitory circuits is considered a major cause of spasticity.
Karen Minassian   +3 more
doaj   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning   +19 more
wiley   +1 more source

Epidural Electrical Stimulation for Functional Recovery in Incomplete Spinal Cord Injury

open access: yesCyborg and Bionic Systems
Epidural electrical stimulation (EES) has emerged as a promising treatment for spinal cord injury (SCI). However, the therapeutic potential of EES in functional recovery following incomplete SCI remains limited, with few studies of a large sample size ...
Yihang Ren   +8 more
doaj   +1 more source

Structural and mechanical alterations in spastic skeletal muscle [PDF]

open access: bronze, 2007
Jared R.H. Foran   +4 more
openalex   +1 more source

Biallelic COL4A2 Variants Associated With Brain Small Vessel Disease and Brain Malformations

open access: yesClinical Genetics, EarlyView.
Biallelic COL4A2 variants cause a spectrum of brain abnormalities such as brain small vessel disease (BSVD). We describe two cases—one with cerebrovascular disruption and one with cortical malformations—expanding the recessive phenotype. Protein modeling reveals destabilization by p.(Arg179Cys), reinforcing its pathogenic role and highlighting collagen
Anees Muhammad   +11 more
wiley   +1 more source

Selective Control Assessment of the Lower Extremity for Infants and Toddlers (Mini‐SCALE): Development and validation of a clinical assessment

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
The development and validation of Mini‐SCALE, an assessment of lower extremity selective motor control for young children 3 months to less than 4 years, is described. Content validity was established by expert opinion, convergent validity was shown by correlation with the Gross Motor subdomain of the DAYC‐2, and scores differed significantly for ...
Loretta A. Staudt   +3 more
wiley   +1 more source

Combined effects of dry needling and exercises therapy on muscle spasticity and motor function in chronic stroke: a pretest-posttest pilot study [PDF]

open access: diamond, 2022
Seyedeh Saeideh Babazadeh-Zavieh   +6 more
openalex   +1 more source

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