Results 221 to 230 of about 25,924 (270)
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MUSCLE GROWTH IN NORMAL AND SPASTIC MICE
Developmental Medicine & Child Neurology, 1984SUMMARYLongitudinal muscle growth was studied in normal and spastic mice. Muscle growth takes place at the musculotendinous junction—the ‘muscle growth‐plate’. In spastic mice muscle growth is reduced by 45 per cent, resulting in contractures.RESUMECroissance musculaire chez les souris normales et spastiquesLa croissance longitudinale du muscle a ...
Nigel Blackburn +3 more
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A model of muscle spasticity in opensim
Gait & Posture, 2013Introduction: Computer simulations of human movement are commonly used to study normal and abnormal gait, for instance of subjects with spasticity. However, they generally do not include explicit models of spasticity. Our goal, therefore, was to develop a computer model of spasticity and to test this model by dynamic simulation of instrumented ...
Jaap Harlaar +6 more
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Spastic Facial Muscle Disorders
2012Facial muscles are a group of striated muscles that, among other things, control facial expression and are innervated by the facial nerve (CNVII). In contrast, the nearby eyelid retractor muscle and masticator muscles are innervated by the oculomotor (CNIII) and mandibular branch of trigeminal nerve (CNV), respectively.
Andrew R. Harrison +2 more
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Treatment of spasticity with muscle afferent block
Neurology, 1999In 1924, Walshe1 first reported that intramuscular injection of diluted procaine reduced muscle rigidity in a patient with postencephalitic parkinsonism. Its mechanism of action was attributed to blockade of muscle afferents because the muscle motor response elicited by electric stimulation was unchanged.
N. Hirota +4 more
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Effect of Muscle Biomechanics on the Quantification of Spasticity
Annals of Biomedical Engineering, 2001The impact of muscle biomechanics on spasticity was assessed by comparison of the reflex responses of the elbow and metacarpophalangeal (MCP) flexor muscles in individuals with chronic spastic hemiplegia following stroke. Specifically, methods were developed to quantify reflex responses and to normalize these responses for comparison across different ...
Brian D. Schmit +2 more
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Muscle Elastography in Multiple Sclerosis Spasticity
Neurodegenerative Disease Management, 2016Ultrasound elastography is a novel imaging modality for evaluating the elasticity of biological tissues. The technique is widely used in oncology to detect and differentiate malignant lesions in soft tissues. Studies have explored use of ultrasound elastography to measure the mechanical properties of muscle in patients with multiple sclerosis ...
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An adapted double threshold protocol for spastic muscles
2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2016The onset of muscle contraction has been an important element in the understanding of human motor control system as well as in the development of medical devices. This task is problematic in the study of spasticity using surface Electromyography (sEMG).
Vieira, Pedro Miguel +3 more
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Developing a quantitative measure of muscle spasticity
IEEE 30th Annual Northeast Bioengineering Conference, 2004. Proceedings of the, 2004Quantitative measurement of spasticity is necessary and can contribute to clinical rehabilitation management, which aims to restore and/or improve function in the affected part of the body. The proposed study shows that by using computerized motional analysis systems, a more quantitative measurement of muscle spasticity can be obtained.
Darnell Simon, Richard A. Foulds
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Update on tizanidine for muscle spasticity and emerging indications
Expert Opinion on Pharmacotherapy, 2008Tizanidine hydrochloride, an alpha(2)-adrenergic receptor agonist, is a widely used medication for the treatment of muscle spasticity. Clinical studies have supported its use in the management of spasticity caused by multiple sclerosis (MS), acquired brain injury or spinal cord injury. It has also been shown to be clinically effective in the management
Edward Garay +2 more
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Botulinum toxin A for spasticity, muscle spasms, and rigidity
Neurology, 1995We studied the effects of botulinum toxin A in 12 patients with spasticity and in eight patients with rigidity. The study design was a double-blind, placebo-controlled crossover trial with botulinum toxin A versus saline. Using the Ashworth Scale for spasticity and the Unified Parkinson's Disease Rating Scale for rigidity, we gave the patients a tone ...
Bahman Jabbari +2 more
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