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Spasticity, muscle, and surgery

2023
Spasticity is a poorly defined concept of increasing resistance against fast movements. It comprises a static picture of lost control on reflexes, and primitive reflexes are unmasked. This view is too simple. Reflexes can be modulated by the individual over time, which means, that increase and decrease are possible.
openaire   +1 more source

Pathology of Spastic Muscle in Cerebral Palsy

Clinical Orthopaedics and Related Research, 1979
The histopathology of muscle in cerebral palsy has not been elucidated because correlated morphologic and biochemical data on normal pediatric muscles are insufficient to allow adequate correlation of pathologic findings. One hundred and eight muscle biopsies were taken during reconstructive operations on 85 patients.
M E, Castle, T A, Reyman, M, Schneider
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Treatment of spasticity with muscle afferent block

Neurology, 1999
In 1924, Walshe1 first reported that intramuscular injection of diluted procaine reduced muscle rigidity in a patient with postencephalitic parkinsonism. Its mechanism of action was attributed to blockade of muscle afferents because the muscle motor response elicited by electric stimulation was unchanged.
T, Mezaki   +4 more
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Spasticity evaluation and management tools

Muscle and Nerve, 2023
Spasticity is a complex and often disabling symptom for patients with upper motor neuron syndromes. Although spasticity arises from neurological disease, it often cascades into muscle and soft tissue changes, which may exacerbate symptoms and further ...
I. Howard, A. Patel
semanticscholar   +1 more source

Muscle histopathology in spastic cerebral palsy

Brain and Development, 1996
We studied the histopathology of spastic muscles in patients with spastic cerebral palsy using specimens obtained from the gastrocnemius muscles during orthopedic operations. Though there was no disease-specific abnormality, we found changes in fiber type distribution, i.e., type-1 fiber predominance and type-2B fiber deficiency. These changes were not
J, Ito   +5 more
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MUSCLE GROWTH IN NORMAL AND SPASTIC MICE

Developmental Medicine & Child Neurology, 1984
SUMMARYLongitudinal muscle growth was studied in normal and spastic mice. Muscle growth takes place at the musculotendinous junction—the ‘muscle growth‐plate’. In spastic mice muscle growth is reduced by 45 per cent, resulting in contractures.RESUMECroissance musculaire chez les souris normales et spastiquesLa croissance longitudinale du muscle a ...
I, Ziv   +3 more
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Effect of Muscle Biomechanics on the Quantification of Spasticity

Annals of Biomedical Engineering, 2001
The impact of muscle biomechanics on spasticity was assessed by comparison of the reflex responses of the elbow and metacarpophalangeal (MCP) flexor muscles in individuals with chronic spastic hemiplegia following stroke. Specifically, methods were developed to quantify reflex responses and to normalize these responses for comparison across different ...
D G, Kamper, B D, Schmit, W Z, Rymer
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Muscle Elastography in Multiple Sclerosis Spasticity

Neurodegenerative Disease Management, 2016
Ultrasound elastography is a novel imaging modality for evaluating the elasticity of biological tissues. The technique is widely used in oncology to detect and differentiate malignant lesions in soft tissues. Studies have explored use of ultrasound elastography to measure the mechanical properties of muscle in patients with multiple sclerosis ...
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Muscle physiology in spasticity and muscle stiffness

Toxicon
This paper examines the physiological changes in spastic muscles contributing to spasticity and muscle stiffness, focusing on the underlying mechanisms and their clinical implications. Spasticity, which is prevalent in neurological conditions such as multiple sclerosis, cerebral palsy, spinal cord injury, stroke, and traumatic brain injury, is ...
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A model of muscle spasticity in opensim

Gait & Posture, 2013
Introduction: Computer simulations of human movement are commonly used to study normal and abnormal gait, for instance of subjects with spasticity. However, they generally do not include explicit models of spasticity. Our goal, therefore, was to develop a computer model of spasticity and to test this model by dynamic simulation of instrumented ...
Marjolein Van der Krogt   +6 more
openaire   +1 more source

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