Results 51 to 60 of about 897,752 (361)

Elevated serum leptin levels are associated with low muscle strength and muscle quality in male patients undergoing chronic hemodialysis

Tzu Chi Medical Journal, 2021
Objectives: Low muscle strength and poor muscle quality are highly prevalent in patients with chronic hemodialysis (HD), which lead to an increased risk of poor clinical outcomes. Leptin dysregulation is common in HD patients. Given that leptin receptors
Bang-Gee Hsu, Chih-Hsien Wang, Yu-Hsien Lai, Chiu-Huang Kuo, Yu-Li Lin   +4 more
doaj   +1 more source

Muscle Strength and Electromyography.

Journal of exercise physiology, 1992
筋の時間的・空間的な収縮特性は、表面筋電図学的な解析によってある程度観測することが可能である。しかし、測定から信号処理までの過程における方法論的な手続きに対する配慮が不十分であると、抽出された情報の実際的な利用価値は低いものになってしまう。そこで、本稿では、表面筋電図学的解析に関する基礎的な情報に関して整理した上で、筋収縮力、筋疲労、筋カトレーニングといった筋収縮特性と表面筋電図との関連性に関して概説する。
openaire   +3 more sources

Influence of Dystrophin Isoform Deficiency on Motor Development in Duchenne Muscular Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In Duchenne muscular dystrophy (DMD), lack of the shorter dystrophin isoforms Dp140 and Dp71 is associated with increased central nervous system (CNS) involvement. We aimed to investigate how CNS involvement affects motor development in young DMD boys.
Mary Chesshyre, Deborah Ridout, Georgia Stimpson, Laurent Servais, Giovanni Baranello, Adnan Manzur, UK NorthStar Clinical Network, M. Scoto, A. Sarkozy, P. Munot, S. Robb, E. Chan, V. Robinson, W. Girshab, V. Crook, E. Milev, L. Abbott, A. Wolfe, E. O’Reilly, J. Watts‐Whent, N. Burnett, R. Thomas, R. Terespolsky, O. Martinaeu, J. Longatto, V. Straub, C. Bettolo, M. Guglieri, J. Diaz‐Manera, G. Tasca, M. Elseed, R. Muni‐Lofra, M. James, D. Moat, J. Sodhi, K. Wong, E. Robinson, E. Groves, R. Rabb, D. Parasuraman, H. McMurchie, H. Chase, Tracey Willis, C. Rylance, N. Birchall, E. Wright, A. Childs, K. Pysden, C. Martos, D. Roberts, L. Pallant, S. Walker, A. Henderson, R. Madhu, R. Karuvattil, Y. Balla, S. Gregson, S. Clark, E. Wraige, H. Jungbluth, V. Gowda, M. Vanegas, J. Sheehan, A. Schofield, C. Smith, I. Hughes, E. Whitehouse, S. Warner, E. Reading, N. Emery, J. Moustoukas, K. Strachan, M. Ong, M. Atherton, N. Mills, S. Sanchez Marco, A. Saxena, K. Skone, J. TeWaterNaude, H. Davis, C. Wood, A. Majumdar, A. Murugan, I. Guarino, R. Tomlinson, H. Jarvis, L. Wills, C. Frimpong, J. Watson, G. Cobb, G. Robertson, P. Brink, J. Burslem, C. Adams, J. Wong, S. Joseph, I. Horrocks, J. Dunne, M. DiMarco, S. Brown, S. McKenzie, K. Torne, R. Mohamed, V. Velmurugan, M. Prasad, S. Sedehizadeh, A. Schugal, R. Keetley, S. Williamson, K. Payne, E. Dowling, P. Fenty, C. de Goede, A. Parkes, K. Baxter, M. Illingworth, N. Bhangu, S. Geary, J. Palmer, K. Shill, S. Tirupathi, A. Shah, D. O’Donogue, J. McVeigh, J. McFetridge, G. Nicfhirleinn, H. Beattie, T. Leyland, K. Stevenson, N. Hussain, D. Baskaran, Z. Lambat, R. Sullivan, L. Locke, G. Ambegaonkar, D. Krishnakumar, J. Taylor, J. Moores, E. Stephen, J. Tewnion, S. Ramdas, M. Sa, A. Skippen, M. Khries, C. Lilien, H. Ramjattan, F. Taylor, H. English, K. Stewart, F. Flint, E. Bartram, R. Noble, Francesco Muntoni   +152 more
wiley   +1 more source

Association between relative muscle strength and cardiovascular disease among middle-aged and older adults in China

BMC Public Health
Background The association between sarcopenia and cardiovascular disease (CVD) is well known. However, the clinical diagnosis of sarcopenia is complex and not suitable for early clinical identification and prevention of CVD. Relative muscle strength (RMS)
Jin-jin Ji, Meng-jie Zhao, Meng-li Xiao, Hui-e Zhang, Qin Tan, Yu-rong Cheng, Fang Lu   +6 more
doaj   +1 more source

Systemic inflammation, body composition, and physical performance in old community-dwellers [PDF]

, 2017
Background Chronic inflammation, changes in body composition, and declining physical function are hallmarks of the ageing process. The aim of the present study was to provide a preliminary characterisation of the relationship among these age-related ...
Addison, Addison, Bandeen-Roche, Buford, Calvani, Cesari, De Martinis, Deng, Dong, Franceschi, Goodpaster, Guralnik, Haehling, Hsu, Hughes, Hughes, Jiang, Jo, Lau, Liao, Marzetti, Marzetti, Marzetti, Opal, Peterson, Prokopchuk, Roubenoff, Seals, Szymańska, Tuttle, Varadhan, Westerhuis, Westerhuis, Zoico   +33 more
core   +2 more sources

Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro, Manuela Dicarlo, Chiara Zecca, Daniele Urso, Maria Teresa Dell'Abate, Davide Vilella, Francesco Borlizzi, Roberta Zerlotin, Angela Oranger, Graziana Colaianni, Silvia Colucci, Maria Grano, Giancarlo Logroscino   +12 more
wiley   +1 more source

Metabolic reprogramming promotes myogenesis during aging [PDF]

, 2019
Sarcopenia is the age-related progressive loss of skeletal muscle mass and strength finally leading to poor physical performance. Impaired myogenesis contributes to the pathogenesis of sarcopenia, while mitochondrial dysfunctions are thought to play a ...
Belli, R, Bonato, A, Caruso, M, Costelli, P, De Angelis, L, Ferraro, E., Leigheb, M, Mirabilii, S, Molfino, A, Muscaritoli, M, Ricciardi, Mr, Tafuri, A   +11 more
core   +3 more sources

Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova, Teresa Fazia, Giovanni Di Caprio, Davide Gentilini, Luisa Bernardinelli, Roberto Bergamaschi   +5 more
wiley   +1 more source

Obesity-associated poor muscle quality: prevalence and association with age, sex, and body mass index

BMC Musculoskeletal Disorders, 2020
Background Muscle quality (i.e., the expression of muscle function per unit of muscle mass) has been proposed as a clinically-relevant measure to detect individuals at risk of functional incapacity.
Pedro L. Valenzuela, Nicola A. Maffiuletti, Gabriella Tringali, Alessandra De Col, Alessandro Sartorio   +4 more
doaj   +1 more source

Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy [PDF]

, 2017
Duchenne muscular dystrophy (DMD) is characterized by muscle degeneration and progressive weakness. There is considerable inter-patient variability in disease onset and progression, which can confound the results of clinical trials.
, Bello, Luca, Gordish-Dressman, Heather, Head, Stewart I., Hoffman, Eric P., Hogarth, Marshall W., Houweling, Peter J., North, Kathryn N., Pegoraro, Elena, Thomas, Kristen C.   +9 more
core   +2 more sources