Results 61 to 70 of about 979,956 (316)

Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) [PDF]

, 2012
BACKGROUND: Laminin-alpha2-deficient congenital muscular dystrophy (MDC1A) is a severe muscle-wasting disease for which no curative treatment is available.
Lin, Shuo, Meinen, Sarina, Ruegg, Markus A.   +2 more
core   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Reference Values of Handgrip and Lower Extremity Strength for Vietnamese Men and Women: The Vietnam Osteoporosis Study

Journal of Cachexia, Sarcopenia and Muscle
Background Falls and sarcopenia are significant public health issues in Vietnam. Despite muscle strength being a critical predictor for these conditions, reference data on muscle strength within the Vietnamese population are lacking. Purpose To establish
Kiet T. Do, Duy K. Hoang, Quan N. Luong, Huy G. Nguyen, An T. Do, Lan T. Ho‐Pham, Tuan V. Nguyen   +6 more
doaj   +1 more source

Relationship between Serum Vitamin D Levels and Muscle Strength in Older Adults: Results of Amirkola Elderly Cohort [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Population aging is a global phenomenon and increase in the number of people over 60 yeas of age proves that the world is aging.
Khadijeh Ezoji, Faezeh Rasulzade Sheikh, Seyed Reza Hosseini, Ali Bijani, Neda Meftah, Kayvan Latifi, Parvin Sajadi Kaboudi   +6 more
doaj  

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Individuals with Recurrent Low Back Pain Exhibit Significant Changes of Paraspinal Muscle Performance after Lumbar Multifidus Intramuscular Fine Wire Electrode Insertion

, 2018
STUDY DESIGN: Case control study. BACKGROUND: Recurrent low back pain (RLBP) is associated with paraspinal muscle dysfunction. Intramuscular electromyography (EMG) is a common tool for studying activation of the deep lumbar paraspinal muscles such as ...
Dinglasan, Vincent, Duong, Anthony, Totten, Russell   +2 more
core   +1 more source

Determinants of inspiratory muscle strength in healthy humans [PDF]

, 2014
We investigated 1) the relationship between the baseline and inspiratory muscle training (IMT) induced increase in maximal inspiratory pressure (PI,max) and 2) the relative contributions of the inspiratory chest wall muscles and the diaphragm (Poes/Pdi ...
Brown, PI, Johnson, MA, Sharpe, GR
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

The Correlation Between Handgrip Strength and Adductor Muscles with Muscle Mass, Fat Mass in the Elderly

Physical Education Theory and Methodology
Background. As you age, body composition will also change, with muscle mass decreasing and fat mass increasing. Handgrip strength and adductor muscle strength have been identified as indicators of older people’s health used to represent overall strength ...
Nur Luthfiatus Solikah, Awang Firmansyah, Nur Shanti Retno Pembayun, Hapsari Shinta Citra Puspita Dewi, Dhevano Taruna Putra Suhadak, Jose V Garcia Jimenez, Muhammad Reza Aziz Prasetya, Andika Bayu Putro   +7 more
doaj   +1 more source