Results 51 to 60 of about 2,474,358 (233)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Relationships between muscle strength and multi-channel surface EMG parameters in eighty-eight elderly

European Review of Aging and Physical Activity, 2018
Background Since age-related muscle strength loss cannot be explained solely by muscle atrophy, other determinants would also contribute to muscle strength in elderly. The present study aimed to clarify contribution of neuromuscular activation pattern to
Kohei Watanabe, Motoki Kouzaki, Madoka Ogawa, Hiroshi Akima, Toshio Moritani   +4 more
doaj   +1 more source

Is it possible to establish reference values for ankle muscle strength? A meta-analytical study. [PDF]

, 2014
BACKGROUND: The importance of measuring ankle muscle strength (AMS) has been demonstrated in a variety of clinical areas. Much data has been accumulated using the Cybex Norm isokinetic dynamometer but a uniform framework does not exist.
Killey, Jennifer, Fish, M, Fish, Michael, Killey, Jenny, Milligan, J, Milligan, James, Killey, J   +6 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Quadriceps muscle strength in scoliosis [PDF]

European Respiratory Journal, 2009
Quadriceps muscle weakness is an important component of chronic obstructive pulmonary disease (COPD). We hypothesised that quadriceps weakness would also be a feature of restrictive lung disease due to scoliosis.We studied 10 patients with severe scoliosis (median (interquartile range (IQR)) forced expiratory volume in 1 s (FEV1)35.3 (11)% predicted ...
Swallow, E.B., Barreiro, E., Gosker, H.R., Sathyapala, S.A., Sanchez, F., Hopkinson, N.S., Moxham, J., Schols, A., Gea, J., Polkey, M.I.   +9 more
openaire   +3 more sources

Changes in Muscle Strength in U19 Soccer Players During an Annual Training Cycle [PDF]

, 2014
The aim of the study was to investigate the seasonal variation in isokinetic strength of the knee flexors and extensors, and conventional (H/QCONV) and functional (H/QFUNC) hamstring to quadriceps strength ratios in highly trained adolescent soccer ...
De Ste Croix, Mark B, Lehnert, Michal, Xaverová, Zuzana   +2 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Association between relative muscle strength and cardiovascular disease among middle-aged and older adults in China

BMC Public Health
Background The association between sarcopenia and cardiovascular disease (CVD) is well known. However, the clinical diagnosis of sarcopenia is complex and not suitable for early clinical identification and prevention of CVD. Relative muscle strength (RMS)
Jin-jin Ji, Meng-jie Zhao, Meng-li Xiao, Hui-e Zhang, Qin Tan, Yu-rong Cheng, Fang Lu   +6 more
doaj   +1 more source

Upper Limb Muscle–Bone Asymmetries and Bone Adaptation in Elite Youth Tennis Players [PDF]

, 2013
Introduction: The study of tennis players allows the nonracket arm to act as an internal control for the exercising racket arm. In addition, the study of the upper limbs removes the influence of gravitational loading, allowing the examination of the ...
Degens H., Ireland A., Cooke, K, Maden-Wilkinson T., McPhee J., Degens, Hans, Maden-Wilkinson, Thomas, Rittweger J., Degens, H., Mcphee, J, Degens, H, Ireland, A., Narici, Marco, Ireland, Alex, McPhee, Jamie, Rittweger, J., Rittweger, Jörn, Ireland, A, Rittweger, J, Maden-Wilkinson, Tom, Narici, M, Narici, M., Cooke, Karl, Cooke, K., Maden-Wilkinson, T, Narici M., McPhee, J., Cooke K.   +27 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source