Results 51 to 60 of about 98,422 (289)
Ergonomics as instrument for prevention against work injury or occupational diseases [PDF]
, 2018 Ergonomics as complex branch solves work of employee on concrete work place and follows up relationships between human, machine and work environment.
Bartlová, Ivana, Koutný, Petr
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Muscle synergy stability and human balance maintenance [PDF]
Journal of NeuroEngineering and Rehabilitation, 2014 The signals that the central nervous system (CNS) produces and sends to the muscles to effect movement are not entirely understood. Muscle synergy theory suggests that the central nervous system produces a small number of signals that pass through a network that distributes combinations of these signals to the muscles. Though these synergies are rather
Wojtara, Tytus +3 more
openaire +2 more sources
α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site. [PDF]
, 2017 Tumors are fibrotic and characterized by abundant, remodeled, and cross-linked collagen that stiffens the extracellular matrix stroma. The stiffened collagenous stroma fosters malignant transformation of the tissue by increasing tumor cell tension to ...
Cassereau, L +11 more
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Estimation of Time-Frequency Muscle Synergy in Wrist Movements
Entropy, 2022 Muscle synergy analysis is a kind of modularized decomposition of muscles during exercise controlled by the central nervous system (CNS). It can not only extract the synergistic muscles in exercise, but also obtain the activation states of muscles to ...
Ping Xie +5 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The case for and against muscle synergies [PDF]
Current Opinion in Neurobiology, 2009 A long standing goal in motor control is to determine the fundamental output controlled by the CNS: does the CNS control the activation of individual motor units, individual muscles, groups of muscles, kinematic or dynamic features of movement, or does it simply care about accomplishing a task?
Matthew C, Tresch, Anthony, Jarc
openaire +2 more sources
iScience, 2019 Summary: Muscular control during walking is believed to be simplified by the coactivation of muscles called muscle synergies. Although significant corticomuscular connectivity during walking has been reported, the level at which the cortical activity is ...
Hikaru Yokoyama +5 more
doaj +1 more source
Age-related differences in adaptation during childhood: The influences of muscular power production and segmental energy flow caused by muscles [PDF]
, 2006 Acquisition of skillfulness is not only characterized by a task-appropriate application of muscular forces but also by the ability to adapt performance to changing task demands.
A Seth +22 more
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source