This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan +6 more
wiley +1 more source
Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai +18 more
wiley +1 more source
De novo-engineered guide RNA-directed transposition with TnpB-family proteins. [PDF]
Schargel RD +6 more
europepmc +1 more source
Neuromorphic Devices and Computing for Sensing, Memory, and Control
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu +2 more
wiley +1 more source
Staged dorsolateral decompression and posterior stabilization for severe ventral odontoid compression in basilar invagination: illustrative case. [PDF]
Jriyasetapong N +2 more
europepmc +1 more source
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang +14 more
wiley +1 more source
A treatment protocol for giant ventral hernias based on predicted postoperative respiratory function. [PDF]
Pérez Lara FJ +6 more
europepmc +1 more source
An Arthroscopic Technique for Hybrid Double-Row Repair Using a Cancellous Screw and Washer for Enhanced Lateral-Row Fixation in Osteoporotic Massive Rotator Cuff Tears With Long-Head Biceps Augmentation. [PDF]
Chawanpaiboon P +4 more
europepmc +1 more source
Developing Orthoplastic Capacity for Soft-tissue Defects via Short-term Training: A Case Series in Samburu County, Kenya. [PDF]
Sciuto D, MacKechnie MC, Terry MJ.
europepmc +1 more source
Supercharged End-to-Side Anterior Interosseous-to-Ulnar Motor Nerve Transfer: A Systematic Review and Meta-analysis. [PDF]
Alghamdi AM +8 more
europepmc +1 more source

