Results 51 to 60 of about 983,311 (294)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Surgical management of long-standing antielevation syndrome after unilateral anterior transposition of the inferior oblique muscle.

, 2014
PURPOSE: To investigate surgical management of patients with long-standing antielevation syndrome following unilateral anterior transposition of inferior oblique muscle.
이종복, 한진우, 한승한, 한소영   +3 more
core   +1 more source

Musique, histoire et société [PDF]

, 2018
Les numéros de la revue Transposition. Musique et sciences sociales nous ont habitués au rythme cyclique d’appels et de parutions sur des thématiques circonscrites.
Talia Bachir-Loopuyt, Bachir-Loopuyt, Talia, Contreras Zubillaga, Igor, Igor Contreras Zubillaga   +3 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Ulnar Nerve Subluxation in the Overhead Athlete: Predicted Loss of Force Following Submuscular Versus Modified Subcutaneous Ulnar Nerve Transposition

Journal of Hand Surgery Global Online
Purpose: Cubital tunnel syndrome and ulnar nerve subluxation are common issues for the overhead athlete and can be a considerable hindrance to their athletic performance. With the care of elite athletes in mind, there must be a balance between the relief
Alexandria A. Bosetti, BS, Eileen M. Colliton, MD, Mark E. Baratz, MD   +2 more
doaj   +1 more source

Superior Rectus Transposition Surgery: Safety, Efficacy, and Place in Therapy

Clinical Ophthalmology, 2022
Mohammad Reza Akbari, Babak Masoomian, Motahhareh Sadeghi, Arash Mirmohammadsadeghi Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranCorrespondence: Arash Mirmohammadsadeghi, Farabi Eye Hospital, Ghazvin Square,
Akbari MR, Masoomian B, Sadeghi M, Mirmohammadsadeghi A   +3 more
doaj  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Posterior Scleritis after Extraocular Horizontal Muscle Transposition Surgery: A Case Report

Beyoglu Eye Journal, 2017
A male patient was diagnosed with bilateral congenital third nerve palsy when he presented at the clinic for the first time in 2001 at the age of 22 with the complaints of decreased visual acuity in the right eye, exodeviation, and movement disability in
Osman Bulut Ocak, Asli Inal, Ebru Demet Aygit, Ihsan Yilmaz, Ahmet Demirok, Birsen Gokyigit   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source