Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane +19 more
wiley +1 more source
Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran +13 more
wiley +1 more source
Cubital tunnel syndrome is often accompanied by paresthesia in ulnar nerve sites and hand muscle atrophy. When muscle weakness occurs, or after failure of more conservative treatments, anterior transposition is used. In the present study, the ulnar nerve
Mei-xiu-li Li +7 more
doaj +1 more source
Ministerial Transposition of EU Directives: Can Oversight Improve Performance? [PDF]
This paper argues that the extent to which national administrations transpose EU directives in a timely fashion may be related to how transposition is coordinated inside national ministries.
Katarina Staronova, Radoslaw Zubek
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Prenatal diagnosis and postnatal follow-up of congenitally corrected transposition of the great arteries and recurrent supraventricular tachycardia [PDF]
The prenatal sonographic diagnosis of congenitally corrected transposition of the great arteries (ccTGA), a rare form of congenital heart disease is very difficult.
Celik, I. +3 more
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ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Post-Accession Transposition and Implementation between Administrative Coordination and Political Bargaining [PDF]
This paper explores the relationship between administrative coordination of EU affairs at the national level and compliance with EU law. First, we develop two hypotheses about the impact of coordination: we expect that the strength of the coordination ...
Dimitrova, Antoaneta
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Anterior transposition of inferior oblique for inferior rectus muscle aplasia
Congenital absence of extraocular muscle is rare. The most common extraocular muscle found to be congenitally absent is superior oblique followed by inferior rectus.
Anupam Singh +5 more
doaj +1 more source
Augmented superior rectus muscle transposition for the treatment of strabismus in Möbius syndrome
Möbius syndrome is a rare congenital disorder characterized by bilateral facial nerve palsy and abducens nerve palsy. It is associated with a wide spectrum of systemic and ocular manifestations; esotropia is commonly the reason for ophthalmic referral ...
Glen A. Gole +3 more
core +1 more source
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