Muscular atrophy, spinal - Open Access .click

Results 131 to 140 of about 72,020 (228)

Nusinersen versus Sham Control in Infantile‐Onset Spinal Muscular Atrophy

New England Journal of Medicine, 2017
R. Finkel +397 more
semanticscholar +1 more source

Docking and Molecular Dynamics Simulation‐Based Analysis of Advanced Small‐Molecule Kinase Inhibitors Identified pre‐let‐7 miRNA Binders

ChemBioChem, Accepted Article.
RNAs play crucial roles in various cellular actions, and the uncontrolled expression or improper folding of RNAs is a cause of many diseases. Certain oncogenic phenotypes stem from the overexpression of regulatory microRNAs that contain secondary structural elements.
Soma Roy, Yang Liu, Peng Wu
wiley +1 more source

Single‐Dose Gene‐Replacement Therapy for Spinal Muscular Atrophy

New England Journal of Medicine, 2017
J. Mendell +25 more
semanticscholar +1 more source

A perspective review of applications of the computed tomography (CT) scan imaging technique for microscopic reservoir rock characterization

Deep Underground Science and Engineering, EarlyView.
In this review, the application of micro‐CT and medical‐CT scanning in the oil and gas industry has been thoroughly discussed. Recent improvements in DRP and modern imaging techniques in the oil and gas industry have been modeled using both experimental and simulation work.
Achinta Bera, Bharadwaj Shukla, Dhruvikkumar Jogani +2 more
wiley +1 more source

Biochemical characteristics and applications of microalga Chlorella sorokiniana KNUA228 isolated from Ulleungdo

Environmental Progress &Sustainable Energy, EarlyView.
Abstract The increasing environmental and health challenges posed by fossil fuel dependency necessitate the exploration of renewable bioresources. Chlorella sorokiniana KNUA228, a microalga isolated from Ulleungdo, Republic of Korea, was investigated to evaluate its biotechnological potential. Molecular analyses confirmed its identity as C. sorokiniana,
Jin‐Won Lee +5 more
wiley +1 more source

Significance of Dynamic Imaging in Diagnosis of Hirayama Disease: A Rare Case Report and Literature Review [PDF]

, 2020
Acosta, Natasha, Kandukuri, Gautham
core +2 more sources

The Physiological Consequences of Bed Rest

, 2007
Bed rest often is used to treat a wide variety of medical conditions. However, bed rest results in profound deconditioning of the body. Bed rest reduces the hydrostatic pressure gradient within the cardiovascular system, reduces muscle force production,
Drury, Daniel G., Stuempfle, Kristin J.
core

Seizures and electroencephalographic findings in inborn errors of metabolism: Clues to differential diagnosis in the neonatal period, infancy, childhood and adolescence, and review of the literature

Epileptic Disorders, EarlyView.
Abstract Although inborn errors of metabolism (IEM) are a rare cause of epilepsy, seizures are a common presentation in these disorders. Seizures in IEM are frequently refractory to conventional anti‐seizure medication and might warrant initiation of specific treatments based on vitamins or dietary modifications or provision of alternative substrates ...
D. Kapoor +7 more
wiley +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola +3 more
wiley +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source

3. good health
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infant

animals
infant, newborn
spinal muscular atrophies of childhood

child, preschool
biology
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