Results 121 to 130 of about 430,112 (309)

Mitochondria and Muscular Diseases [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1982
D. Hayes, J. Clark
openaire   +2 more sources

Slow gait speed for two years, weakness of lower limbs for one year

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
DOI：10.3969/j.issn.1672-6731.2019.09 ...
Hao WU, Zhi-hong SHI, Tong HAN, YAN Xiao-ling, Yong JI   +4 more
doaj  

Facts about Wildlife Diseases: Capture Myopathy in Farmed White-Tailed Deer

EDIS
This publication discusses causes, clinical signs, and ways to reduce risk of capture myopathy in farmed white-tailed deer. Written by Juan M. Campos Krauer, and published by the Veterinary Medicine—Department of Large Animal Clinical Sciences, UF/IFAS ...
Juan Manuel Campos Krauer
doaj   +1 more source

Does macronutrient consumption affect aerobic capacity? [PDF]

, 2019
Background: Fitness in the United States is declining as the prevalence of obesity rises. It is known generally that exercise and diet both play a part in becoming fit, therefore veering away from being obese and/or overweight.
Bush-Means, Jordan
core   +2 more sources

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Critical illness polyneuromyopathy in septic patients: Is it possible to diagnose it in a bedside clinical examination?

Arquivos de Neuro-Psiquiatria
Objective: To determine the sensitivity and specificity of peripheral and respiratory muscle strength tests in diagnosing critical illness polyneuromyopathy (CIPNM), compared with an electrophysiological examination.
Débora Schmidt, Ana Cláudia Coelho, Fernando Nataniel Vieira, Vitor Félix Torres, Augusto Savi, Silvia Regina Rios Vieira   +5 more
doaj   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Molecular mechanisms underlying the ferroptosis-induced epileptiform activity in mouse cortical slices

Frontiers in Cellular Neuroscience
IntroductionFerroptosis, a newly defined iron-dependent programmed cell death, characterized by excessive accumulation of lipid peroxides and reactive oxygen species, is involved in epilepsy, particularly in those forms resistant to drugs.
Sara Petrillo, Federica Loia, Michela Giustizieri, Caterina Torda, Sara Cairoli, Bianca Goffredo, Marina Trivisano, Luca de Palma, Federico Vigevano, Nicola Specchio, Nicola Specchio, Enrico Cherubini, Fiorella Piemonte   +12 more
doaj   +1 more source