Results 131 to 140 of about 54,763 (333)
New insights into applications of base editor in hereditary disorders
Interdisciplinary Medicine, EarlyView.Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai +8 more
wiley +1 more source
Progressive Muscular Atrophy Associated with Primary Muscular Dystrophy in the Second Generation [PDF]
, 1913 Arthur F. Hertz, Wendy Johnson
openalex +1 more source
JCPP Advances, EarlyView.Abstract Background Health anxiety (HA) is characterized by impairing worry about being or becoming seriously ill. This cross‐sectional study aimed to explore psychological and behavioral correlates of HA compared to other anxiety phenomena in adolescents, that is, with respect to depression, physical symptoms, bodily dissatisfaction, health‐related ...
Charlotte Steen Duholm +6 more
wiley +1 more source
Targeting Nfix to fix muscular dystrophies
Cell Stress, 2017 Muscular dystrophies (MDs) are still incurable heterogeneous diseases, characterized by muscle wasting, replacement by fibrotic tissue, and increasing weakness, which in severe cases, such as Duchenne MD, lead to premature death. MDs are due to mutations
Giuliana Rossi +2 more
doaj +1 more source
α-Tocopherol Requirement of the Rat for Reproduction in the Female and Prevention of Muscular Dystrophy in the Young [PDF]
, 1941 Marianne Goettsch, A. M. Pappenheimer
openalex +1 more source
Microscopy Research and Technique, EarlyView.This study presents the light sheet fluorescence microscopy (LSFM) as a tool for 3D‐imaging of whole skeletal muscle to reveal satellite cells (SCs), the muscle stem cells that activate following damage to repair injured tissue. After tissue clearing and whole‐mount staining process aimed to enable optical access and specific cell labeling (1), murine ...
Rachele Garella +11 more
wiley +1 more source
Cardiomyopathies and Arrythmias in Neuromuscular Diseases
CardiogeneticsNeuromuscular diseases (NMDs) encompass various hereditary conditions affecting motor neurons, the neuromuscular junction, and skeletal muscles. These disorders are characterized by progressive muscle weakness and can manifest at different stages of life,
Giuseppe Sgarito +9 more
doaj +1 more source
The Heart in Progressive Muscular Dystrophy [PDF]
, 1951 Jacob Zatuchni +3 more
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Journal of General and Family Medicine, EarlyView.Abstract Objectives This narrative review identifies pitfalls in managing constipation in older adults and provides evidence‐based recommendations to avoid them. Methods A selective literature search was conducted across electronic databases (PubMed, MEDLINE, Embase, and Cochrane Library) to identify relevant publications on constipation management in ...
Madunil Niriella +3 more
wiley +1 more source