Results 11 to 20 of about 343,838 (345)
Delivery of genetic medicines for muscular dystrophies [PDF]
Cell Reports MedicineSummary: Muscular dystrophies are a group of heterogenic disorders characterized by progressive muscle weakness, the most common of them being Duchenne muscular dystrophy (DMD).
Yulia Chulanova, Dor Breier, Dan Peer
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The association between oxidative balance score and muscular dystrophies [PDF]
Frontiers in NutritionIntroductionThis research utilized data from the NHANES 2011–2018 study to investigate the connection between the Oxidative Balance Score (OBS) and muscular dystrophies.MethodsThis study is a cross-sectional, observational, secondary analysis utilizing ...
Dupeng Tang +3 more
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Misregulation of the Ubiquitin–Proteasome System and Autophagy in Muscular Dystrophies Associated with the Dystrophin–Glycoprotein Complex [PDF]
CellsThe stability of the sarcolemma is severely impaired in a series of genetic neuromuscular diseases defined as muscular dystrophies. These are characterized by the centralization of skeletal muscle syncytial nuclei, the replacement of muscle fibers with ...
Manuela Bozzi +3 more
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Transcriptomic gene signatures measure satellite cell activity in muscular dystrophies [PDF]
iScienceSummary: The routine need for myonuclear turnover in skeletal muscle, together with more sporadic demands for hypertrophy and repair, are performed by resident muscle stem cells called satellite cells.
Elise N. Engquist +5 more
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Pediatrics In Review, 2000 Muscular dystrophy is a group of genetically determined muscular disorders marked by progressive wasting and weakness of the skeletal muscle, but which often affect cardiac and smooth muscles or other tissues. The patterns of inheritance are either dominant or recessive although the gene may be defective because of a new mutation.
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Correction of muscular dystrophies by CRISPR gene editing.
Journal of Clinical Investigation, 2020 Muscular dystrophies are debilitating disorders that result in progressive weakness and degeneration of skeletal muscle. Although the genetic mutations and clinical abnormalities of a variety of neuromuscular diseases are well known, no curative ...
F. Chemello, R. Bassel-Duby, E. Olson
semanticscholar +1 more source
Stem cell therapy for muscular dystrophies.
Journal of Clinical Investigation, 2020 Muscular dystrophies are a heterogeneous group of genetic diseases, characterized by progressive degeneration of skeletal and cardiac muscle. Despite the intense investigation of different therapeutic options, a definitive treatment has not been yet ...
S. Biressi, A. Filareto, T. Rando
semanticscholar +1 more source
The care of patients with Duchenne, Becker, and other muscular dystrophies in the COVID‐19 pandemic
Muscle and Nerve, 2020 The coronavirus disease 2019 (COVID‐19) pandemic has resulted in the reorganization of health‐care settings affecting clinical care delivery to patients with Duchenne and Becker muscular dystrophy (DBMD) as well as other inherited muscular dystrophies ...
A. Veerapandiyan +14 more
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Mouse models for muscular dystrophies: an overview
Disease Models & Mechanisms, 2020 Muscular dystrophies (MDs) encompass a wide variety of inherited disorders that are characterized by loss of muscle tissue associated with a progressive reduction in muscle function.
M. van Putten +5 more
semanticscholar +1 more source
Role of Immunoglobulins in Muscular Dystrophies and Inflammatory Myopathies
Frontiers in Immunology, 2021 Muscular dystrophies and inflammatory myopathies are heterogeneous muscular disorders characterized by progressive muscle weakness and mass loss. Despite the high variability of etiology, inflammation and involvement of both innate and adaptive immune ...
Andrea Farini +4 more
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