Results 191 to 200 of about 55,853 (286)

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Noninvasive 11.7‐T Magnetic Resonance Spectroscopy and Imaging Reveals Retinal Metabolic Alterations Induced by Blue Light Exposure

NMR in Biomedicine, Volume 39, Issue 3, March 2026.
Retinal metabolic changes were analyzed using proton magnetic resonance spectroscopy (1H‐MRS), marking an initial application of this non‐invasive method on living eyes. Key metabolites were identified within the retinal region of adult rats. The observed changes following intense blue light exposure were predominantly attributable to the retina, as it
Lacramioara Samoila, Alexandru Farcasanu, Simion Simon, Ede Bodoki, Ovidiu Samoila, Oliviu Vostinaru, Elena Dinte, Andreea Elena Bodoki, Dan Iudean, Calin Muresan, Simona Clichici   +10 more
wiley   +1 more source

Circular RNAs and their emerging roles in muscular immune-related diseases. [PDF]

Front Immunol
Urzi F, Srpčič A, Lakota K.
europepmc   +1 more source

No General Association Between Myositis Antibodies and Electromyography Findings

Neurology and Clinical Neuroscience, Volume 14, Issue 2, Page 160-167, March 2026.
ABSTRACT Objective Myositis‐specific antibodies (MSAs), myositis‐associated antibodies (MAAs), and concentric needle electromyography (EMG) are routinely used in the differential diagnosis of myositis. Their mutual relationship, particularly between MSAs/MAAs and EMG findings, remains unclear.
Benedict Kleiser, Hanna Seifermann, David Hoffmann, Markus C. Kowarik, Evelyn Dubois, Marcel Armbruster, Alexander Grimm, Justus Marquetand   +7 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, Volume 22, Issue 16, 17 March 2026.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Dystrophic Skeletal Muscle Phenotypes Can Be Horizontally Transferred via Fecal Microbiome Transplantations. [PDF]

FASEB J
Butcher J, Gosse JT, Gobin J, Ravel-Chapuis A, Jasmin BJ, Stintzi A.   +5 more
europepmc   +1 more source

Emergence, Challenges, and Opportunities for Chiral Nanocellulose Assemblies in Tissue Engineering and Wound Healing

Small Structures, Volume 7, Issue 3, March 2026.
This review explores chiral nanomaterials for tissue engineering and wound healing, specifically focusing on the potential of nanocellulose. The inherent chirality of nanocelluloses and their assemblies enables the creation of biomimetic scaffolds with unique biological interactions. Chiral nematic self‐assembly of cellulose nanocrystals, in particular,
Mahboubeh Nabavinia, Hossein Khanjanzadeh, Asier R. Muguruza, Anna Roig, Erlantz Lizundia, Justin O. Zoppe   +5 more
wiley   +1 more source

Complement C5 Inhibitor Ameliorates a Case of Dysferlinopathy. [PDF]

Neurol Neuroimmunol Neuroinflamm
Kang S, Wang Q, Lv H, Deng J, Zhang W, Lu X, Yuan Y, Wang Z, Zheng F, Yu M.   +9 more
europepmc   +1 more source

Parental counselling and autopsy results: A retrospective diagnostic cohort study at a multidisciplinary fetal neurology clinic

Developmental Medicine &Child Neurology, Volume 68, Issue 3, Page 441-452, March 2026.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.70022 This original article is commented on by Scelsa on pages 311–312 of this issue. Abstract Aim To examine the accuracy of prenatal counselling at a multidisciplinary fetal neurology clinic (FNC) that led to termination of pregnancy (TOP), to improve the quality of future ...
Avi Shariv, Michal Gafner, Zvi Leibovitz, Letizia Schreiber, Dvora Kidron, Ayala Arad, Efrat Hadi, Stephanie Libzon, Liat Ben Sira, Maya Goldschmidt Manor, Dorit Lev, Tally Lerman‐Sagie, Liat Gindes   +12 more
wiley   +1 more source

Exploring Desmin as a Potential Modifier in Duchenne Muscular Dystrophy-Associated Cardiomyopathy. [PDF]

Acta Physiol (Oxf)
Guennec BE, Hovhannisyan Y, Revet G, Polat S, Hassani M, Mougenot N, Barthelemy I, Blot S, Cieniewski-Bernard C, Ferry A, Kordeli E, Li Z, Agbulut O.   +12 more
europepmc   +1 more source