Results 201 to 210 of about 55,853 (286)

Muscle MRI and Muscle Ultrasound Applications in MND/ALS: Academic Insights and Clinical Opportunities

European Journal of Neurology, Volume 33, Issue 3, March 2026.
ABSTRACT Background There is an unmet need for the clinically relevant ALS biomarkers to facilitate an accurate diagnosis in suspected cases, monitor disease progression and evaluate response to therapy in clinical trials. While the MND/ALS literature is dominated by innovative brain studies, motor disability in ALS is primarily driven by neurogenic ...
Alison Toomey, Jana Kleinerova, Ee Ling Tan, We Fong Siah, Peter Bede   +4 more
wiley   +1 more source

Whole-exome sequencing identifies TRIM72 as a candidate gene for autosomal recessive limb-girdle muscular dystrophy. [PDF]

Hum Genomics
Tlili A, Al Mutery A.
europepmc   +1 more source

Bioengineered AAV9 and Optimised Microdystrophin Vectors Augment Phenotypic Rescue in a Murine Model of Duchenne Muscular Dystrophy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 5, March 2026.
ABSTRACT Duchenne muscular dystrophy (DMD) is a severe neuromuscular disorder without an effective cure. Adeno‐associated virus (AAV) based gene therapy has improved dystrophin function, with sub‐optimal clinical outcomes. We reasoned that a combination of rational engineering of AAV9 capsids modified at the post‐translational modification sites ...
Mohankumar B. Senthilkumar, Sanya Sharma, Navaneeth Srinivasan, Anila Varghese, Pratiksha Sarangi, Vijayata Singh, Narendra Kumar, Devyani Yenurkar, Sudip Mukherjee, Sonal Amit, Sameer Bhatia, Santosh K. Misra, Ratna Dua Puri, Jeffrey Chamberlain, Giridhara R. Jayandharan   +14 more
wiley   +1 more source

Selenoprotein N and SEPN1-Related Myopathies: Mechanisms, Models, and Therapeutic Perspectives. [PDF]

Biomolecules
Lanza M, Zito E, Dinoi G, Buono AV, De Luca A, Imbrici P, Liantonio A, Conte E.   +7 more
europepmc   +1 more source

The Role of MEF2 in Scar Formation and Angiogenesis

Journal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
ABSTRACT Background Myocyte enhancer factor 2 (MEF2), belonging to the Minichromosome Maintenance 1, Agamous, Deficiens and Serum Response Factor (MADS) box family with four members (MEF2A‐D), plays a pivotal role in the proliferation and differentiation of various cells, including endothelial cells (ECs) and fibroblasts, as well as in physiological ...
Rui Tao, Yajuan Song, Zhou Yu, Yankun Guo, Yuye Cao, Tong Wang, Peng Guo, Yue Yin   +7 more
wiley   +1 more source

Rethinking Corticosteroid Therapy in Pediatric Neurology. [PDF]

J Inflamm Res
Lin WS.
europepmc   +1 more source

[Model animals for muscular dystrophy].

Experimental animals, 2003
openaire   +1 more source

A Dominant Founder Lineage Has Possible Fitness Costs for the Endangered Mexican Grey Wolf

Molecular Ecology, Volume 35, Issue 5, March 2026.
ABSTRACT The Mexican grey wolf (Canis lupus baileyi) is an endangered and genetically distinct subspecies of grey wolf adapted to the warm climates of the southwestern United States and Mexico. Following centuries of eradication efforts, Mexican grey wolves were protected under the Endangered Species Act in 1976, prompting an international ex situ ...
Yeraldi Loera, Manisha Khakoo, Emily Krueckeberg, Ingrid G. Nilsson, Zehao Wu, Maggie Dwire, Jennifer Adams, Lisette Waits, John K. Oakleaf, Mariel L. Campbell, Jonathan L. Dunnum, Joseph A. Cook, Bridgett M. vonHoldt   +12 more
wiley   +1 more source

Feasibility and Safety of Argon Cold Plasma Use as an Adjunctive Treatment for Corneal Disease in Dogs, Cats and Small Mammals: A Prospective Clinical Study

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Objective Evaluation of the feasibility of argon cold plasma (ACP) use in corneal diseases in clinical practice and assessment of short‐ and long‐term safety in dogs, cats, and small mammals. Animals Studied Client‐owned animals. Procedure ACP was performed in animals with corneal diseases using the kINPenVET (Neoplas GmbH, Germany) under ...
Petr Soukup, Ingrid Allgoewer
wiley   +1 more source

Muscle-specific increased expression of <i>JAG1</i> improves the skeletal muscle phenotype in dystrophin-deficient mice. [PDF]

Proc Natl Acad Sci U S A
de Souza Leite F, Lambert MR, Zhang TY, Conner JR, Paulo JA, Oliveira SF, Guha Thakurta S, Bowles J, Gussoni E, Gygi SP, Widrick JJ, Kunkel LM.   +11 more
europepmc   +1 more source