Results 201 to 210 of about 157,656 (310)

Senolytics and exercise: Dual modalities for rejuvenating muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican   +4 more
wiley   +1 more source

The mitochondrial‐targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial‐apoptotic but not necroptotic signalling during ovarian cancer

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar   +15 more
wiley   +1 more source

Direct AMPK Activation Confers Mutation-Independent Therapeutic Benefit in Duchenne Muscular Dystrophy. [PDF]

open access: yesJ Cachexia Sarcopenia Muscle
Ng SY   +12 more
europepmc   +1 more source

Fat/Water Separation at 7 T Using a 3D Radial Sequence With Quasi‐Continuous Echo Times

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 1, Page 96-108, July 2026.
ABSTRACT Purpose To achieve a reliable fat/water separation (FWS) at 7 T using a new 3D radial sequence and reconstruction workflow with quasi‐continuous TE sampling. Methods A 3D radial density‐adapted sequence with quasi‐continuous TE sampling was developed for a 7 T whole‐body MRI system.
Matthias Rohe   +9 more
wiley   +1 more source

MyomiRs Expression in Limb Girdle Muscular Dystrophy. [PDF]

open access: yesIUBMB Life
Breveglieri G   +7 more
europepmc   +1 more source

RIPK3 Inhibition Mitigates Denervated Muscle Atrophy via NOX4‐Mediated Mitochondrial Restoration and Inflammation Suppression

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Peripheral nerve injury‐induced muscle atrophy shares core pathophysiological features with systemic wasting disorders including cachexia and sarcopenia, yet early molecular triggers remain undefined. This study investigates the pathogenic role of receptor‐interacting protein kinase 3 (RIPK3) in denervation atrophy.
Yuntian Shen   +6 more
wiley   +1 more source

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