Senolytics and exercise: Dual modalities for rejuvenating muscle
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
Abstract figure legend An evaluation of the degree to which mitochondrial hydrogen peroxide emission (mH2O2)‐mediated apoptotic and necroptotic signalling contributes to skeletal muscle atrophy in an orthotopic epithelial ovarian cancer (EOC) model. To determine whether attenuating mH2O2 could prevent regulated cell death signalling and mitigate muscle
Shahrzad Khajehzadehshoushtar +15 more
wiley +1 more source
Management of adrenal insufficiency risk after long-term systemic glucocorticoid therapy in Duchenne muscular dystrophy: Clinical practice recommendations [PDF]
Bowden, Sasigarn A +3 more
core +1 more source
Correction to: Task-based effective connectivity finds alterations in frontoparietal network in Duchenne muscular dystrophy. [PDF]
europepmc +1 more source
Direct AMPK Activation Confers Mutation-Independent Therapeutic Benefit in Duchenne Muscular Dystrophy. [PDF]
Ng SY +12 more
europepmc +1 more source
Fat/Water Separation at 7 T Using a 3D Radial Sequence With Quasi‐Continuous Echo Times
ABSTRACT Purpose To achieve a reliable fat/water separation (FWS) at 7 T using a new 3D radial sequence and reconstruction workflow with quasi‐continuous TE sampling. Methods A 3D radial density‐adapted sequence with quasi‐continuous TE sampling was developed for a 7 T whole‐body MRI system.
Matthias Rohe +9 more
wiley +1 more source
Muscle MRI in patients with dysferlinopathy: Pattern recognition and implications for clinical trialP [PDF]
et al,, Harms, Matthew, Pestronk, Alan
core +1 more source
MyomiRs Expression in Limb Girdle Muscular Dystrophy. [PDF]
Breveglieri G +7 more
europepmc +1 more source
Redefining the role of the transfusion medicine physician in the era of advanced cellular therapies
Transfusion, EarlyView.
Eric A. Gehrie, Kevin J. Land
wiley +1 more source
ABSTRACT Background Peripheral nerve injury‐induced muscle atrophy shares core pathophysiological features with systemic wasting disorders including cachexia and sarcopenia, yet early molecular triggers remain undefined. This study investigates the pathogenic role of receptor‐interacting protein kinase 3 (RIPK3) in denervation atrophy.
Yuntian Shen +6 more
wiley +1 more source

