Results 41 to 50 of about 3,722 (122)

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Matsuoka Nonlinear Oscillator Integration for Investigating Parkinsonian Tremor Dynamics through Multibody Simulation

Parkinson's disease (PD) stands as a relentless neurodegenerative condition marked by a cascade of motor symptoms, such as tremors, rigidity, and bradykinesia. Among these manifestations, tremor emerges as a central feature, exerting a profound impact on
Pellicano F., Zippo A.
core   +1 more source

Redox‐regulated signalling of adaptations to contractile activity in skeletal muscle: Implications for age‐related muscle weakness

Experimental Physiology, EarlyView.
Abstract Skeletal muscle adaptation to contractile activity is modulated by redox signalling, primarily through reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). Early research framed ROS as deleterious byproducts of exercise, but subsequent studies have established their roles as signalling molecules involved in mitochondrial biogenesis,
Malcolm J. Jackson
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

From Prevention to Healthy Longevity: Evaluating the Multi‐Systemic Effects of Physical Activity and Lifestyle Behaviours in Women

Reproductive, Female and Child Health, Volume 5, Issue 4, December 2026.
ABSTRACT Purpose Despite spending more on healthcare than any other high‐income nation, the United States faces comparatively poor life expectancy outcomes, primarily due to non‐compliance with preventable and modifiable lifestyle behaviours. This review evaluates the multi‐systemic benefits of physical activity, exercise, diet, weight management and ...
Darah Dilmaghani, Mary Collins, Gloria A. Bachmann   +2 more
wiley   +1 more source

Performances and Fatigue Responses to Weighted Vest Training in Parkour Novices

European Journal of Sport Science, Volume 26, Issue 10, October 2026.
ABSTRACT Weighted vest training has demonstrated benefits for muscle strength, which is critical for parkour performance. However, the acute effects of external loading in this discipline remain poorly understood. This study investigated the impact of weighted vest use during parkour sessions on lower‐limb performance, perceived exertion, and muscle ...
Sidney Grosprêtre, Philémon Marcel‐Millet, Pauline Eon, Lucas Garbellotto, Bart Roelands, Kevin De Pauw   +5 more
wiley   +1 more source

Two‐Photon Fluorescence and Second‐Harmonic Generation Microscopy: Principles and Biomedical Applications

Journal of Biophotonics, Volume 19, Issue 10, October 2026.
Compared with single‐photon methods, TPM enables deep‐tissue imaging using near‐infrared light, with excitation confined to the focal plane, thereby reducing photodamage. SHG microscopy images noncentrosymmetric biological structures such as collagen and myosin without fluorescent labels, offering direct structural contrast.
Kausalya Neelavara Makkithaya, Gagan Raju, Subir Das, Ajeetkumar Patil, Rajesh Kumar, Yury V. Kistenev, Guan‐Yu Zhuo, Nirmal Mazumder   +7 more
wiley   +1 more source

A study of engagement in casual leisure occupations by individuals who are living with neuropalliative conditions

, 2013
Purpose. This study explored the following research questions:1. What are the normal and sensory-overloaded behaviours exhibited by adults living with neuropalliative conditions?2.
Fenech, Anne
core   +1 more source

Effects of Daily Rhythm‐Aligned Training on Skeletal Muscle Adaptation in Older Adults: A Randomized Controlled Trial

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Ageing is associated with declines in skeletal muscle mass and strength, increasing the risk of sarcopenia, functional impairment and reduced quality of life. Resistance training is an effective intervention to counteract these changes.
Fabienne Bruggisser, Soraya Ritter, Ralf Roth, Egbert T. Ritter, Denis Infanger, Romina Ledergerber, Timo Hinrichs, Frank A. J. L. Scheer, Christoph Handschin, Henner Hanssen, Raphael Knaier   +10 more
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source