Results 71 to 80 of about 13,530 (178)

Exploring Cognitive, Behavioral, and Psychological Dimensions in Persistent Idiopathic Facial Pain and Other Chronic Orofacial Pain Conditions

Brain and Behavior, Volume 16, Issue 4, April 2026.
This case‐control study assessed 42 chronic orofacial pain patients, including 23 patients with persistent idiopathic facial pain, and 42 controls. COPc patients showed cognitive deficits, mood symptoms, alexithymia, and maladaptive coping, especially catastrophizing.
Alessandra Telesca, Danilo Antonio Montisano, Susanna Usai, Veronica Faltracco, Alessia Ferrario, Giulia Gandini, Licia Grazzi, Giuseppe Lauria Pinter, Monica Consonni   +8 more
wiley   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

USSR Space Life Sciences Digest, issue 16 [PDF]

This is the sixteenth issue of NASA's USSR Life Sciences Digest. It contains abstracts of 57 papers published in Russian language periodicals or presented at conferences and of 2 new Soviet monographs.
Donaldson, P. Lynn, Hooke, Lydia Razran, Leveton, Lauren B., Rowe, Joseph, Siegel, Bette, Teeter, Ronald   +5 more
core   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

MedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai, Chongxiang Wang, Ping Jiang, Xiaopeng Mei   +3 more
wiley   +1 more source

Quantitative Susceptibility Mapping in Skull Base Chordoma: In Silico Analysis and In Vivo Application Towards Indirect Hypoxia Assessment

Magnetic Resonance in Medicine, Volume 95, Issue 4, Page 2092-2105, April 2026.
ABSTRACT Purpose To evaluate quantitative susceptibility mapping (QSM) beyond the brain through realistic simulations and to explore preliminary evidence that may be indicative of hypoxia in skull base chordomas (SBC). Methods Each step of the QSM pipeline was optimized within an in silico framework consisting of (i) phase unwrapping, (ii) background ...
P. Fenech, L. Morelli, G. Parrella, S. Imparato, A. Iannalfi, S. Lillo, E. Orlandi, G. Baroni, C. Paganelli   +8 more
wiley   +1 more source

Acute Effect of Inspiratory Muscle Training on Peripheral Tissue Oxygenation Behavior in Individuals With COPD: A Randomized Crossover Study

Physiotherapy Research International, Volume 31, Issue 2, April 2026.
ABSTRACT Background and Purpose Chronic Obstructive Pulmonary Disease (COPD) is a pulmonary condition characterized by airflow obstruction, which progresses with systemic alterations such as changes in muscle composition and metabolism, anticipating the activation of the inspiratory metaboreflex.
Natália Mota da Silva Borges, Dyego Tavares de Lima, Arthur Bruno de Abreu Morais, Laura Natália Freitas Cavalcante Tenório, Sandyelle Teixeira Vieira, Hellen Maria Lacerda de Oliveira Carneiro, Annicia Lins Freitas, Daniele Ferreira de Santana Silva, Elysson da Silva, Maria Anita Oliveira Souza Paiva, José Vinicius Bulhões da Silva, Kauane Paulino Guedes, Tatiana Onofre Gama, Ana Tereza do Nascimento Sales Figueiredo Fernandes, Ingrid Guerra Azevedo, Pollyana Soares de Abreu Morais, Danielle Aparecida Gomes Pereira, Rafaela Pedrosa, José Heriston de Morais Lima, Eduardo Eriko Tenório de França   +19 more
wiley   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Human metabolic adaptations and prolonged expensive neurodevelopment: A review [PDF]

, 2008
1. After weaning, human hunter-gatherer juveniles receive substantial (≈3.5-7 MJ day^-1^), extended (≈15 years) and reliable (kin and nonkin food pooling) energy provision. 2. The childhood (pediatric) and the adult human ...
John R. Skoyles
core   +2 more sources

Daytime Sleepiness and Dispositional Optimism Are Related to Awake Bruxism Among Patients With Painful Temporomandibular Disorders

Journal of Oral Rehabilitation, Volume 53, Issue 4, Page 833-842, April 2026.
Daytime sleepiness and dispositional optimism are related with awake bruxism among patients with painful temporomandibular disorders. ABSTRACT Objective Awake bruxism (AB) is a multifactorial condition that has been linked to several physiological and psychological factors.
Bachar Reda, Frank Lobbezoo, Daniele Manfredini, Maurits K. A. van Selms   +3 more
wiley   +1 more source