Objective Metabolic syndrome (MetS) is a known comorbidity of psoriatic arthritis (PsA) and is associated with PsA disease activity. We aimed to explore the association between MetS and radiographic features (peripheral and axial) in PsA. Methods We included patients with PsA followed at our prospective observational cohort for the period between 1978 ...
Fadi Kharouf+6 more
wiley +1 more source
Bruton tyrosine kinase inhibitors in the management of Waldenström macroglobulinemia
Abstract Bruton tyrosine kinase (BTK) inhibitors have taken a central role in the management of patients with Waldenström macroglobulinemia and are the only agents approved by the Food and Drug Administration (FDA) to treat these patients. Although associated with high rates of durable responses, unmet needs with BTK inhibitor therapy include ...
Jorge J. Castillo+4 more
wiley +1 more source
Stride Length Estimation with Deep Learning [PDF]
Accurate estimation of spatial gait characteristics is critical to assess motor impairments resulting from neurological or musculoskeletal disease. Currently, however, methodological constraints limit clinical applicability of state-of-the-art double integration approaches to gait patterns with a clear zero-velocity phase.
arxiv +1 more source
EFFECTS OF PROBODY MASSAGE ON PHYSICAL CHARACTERISTICS, BODY ALIGNMENT IN THE MIDDLE-AGED WOMEN WITH MUSCULOSKELETAL DISEASES [PDF]
The purpose of this study was to investigate the degree of improvement of physical characteristics, body alignment of the exercise group after Probody Massage Program of 8 weeks with 30 musculoskeletal diseases in middle-aged Women in B Metropolitan city.
Lee, Bom-Jin+3 more
core +1 more source
Mutation Screening Using Automated Bidirectional Dideoxy Fingerprinting
The need continues to grow for mutation identification in genetic disease in both research and clinical settings. We have developed a rapid nonradioactive bidirectional dideoxy fingerprint mutation screening procedure that is performed using an automated
Yuriy O. Shevchenko+2 more
doaj +1 more source
Objective The aim of this study was to apply sequence analysis (SA) to phenotype health care patterns of adult patients with musculoskeletal (MSK) conditions using primary care electronic health records and to investigate the association between these health care patterns and patients’ self‐reported outcomes after consultation.
Smitha Mathew+6 more
wiley +1 more source
Birth defects associated with paternal firefighting in the National Birth Defects Prevention Study
Abstract Background Few studies have evaluated birth defects among children of firefighters. We investigated associations between birth defects and paternal work as a firefighter compared to work in non‐firefighting and police officer occupations. Methods We analyzed 1997–2011 data from the multi‐site case‐control National Birth Defects Prevention ...
Miriam R. Siegel+7 more
wiley +1 more source
A Lightweight CNN and Joint Shape-Joint Space (JS2) Descriptor for Radiological Osteoarthritis Detection [PDF]
Knee osteoarthritis (OA) is very common progressive and degenerative musculoskeletal disease worldwide creates a heavy burden on patients with reduced quality of life and also on society due to financial impact. Therefore, any attempt to reduce the burden of the disease could help both patients and society.
arxiv
Learning to Estimate Critical Gait Parameters from Single-View RGB Videos with Transformer-Based Attention Network [PDF]
Musculoskeletal diseases and cognitive impairments in patients lead to difficulties in movement as well as negative effects on their psychological health. Clinical gait analysis, a vital tool for early diagnosis and treatment, traditionally relies on expensive optical motion capture systems.
arxiv
Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force [PDF]
Background: Therapeutic targets have been defined for diseases like diabetes, hypertension or rheumatoid arthritis and adhering to them has improved outcomes. Such targets are just emerging for spondyloarthritis (SpA). Objective: To define the treatment
Baraliakos, Xenofon+31 more
core +2 more sources