Results 101 to 110 of about 2,495,332 (299)

SMPDL3B a novel biomarker and therapeutic target in myalgic encephalomyelitis

Journal of Translational Medicine
Background Sphingomyelin phosphodiesterase acid-like 3B (SMPDL3B) is emerging as a potential biomarker and therapeutic target in myalgic encephalomyelitis (ME), a complex multisystem disorder characterized by immune dysfunction, metabolic disturbances ...
Bita Rostami-Afshari, Wesam Elremaly, Anita Franco, Mohamed Elbakry, Marie-Yvonne Akoume, Ines Boufaied, Atefeh Moezzi, Corinne Leveau, Pierre Rompré, Christian Godbout, Olav Mella, Øystein Fluge, Alain Moreau   +12 more
doaj   +1 more source

The Role of Nuclear and Mitochondrial DNA in Myalgic Encephalomyelitis: Molecular Insights into Susceptibility and Dysfunction

DNA
Myalgic Encephalomyelitis (ME), also known as chronic fatigue syndrome (CFS), is a debilitating and heterogeneous disorder marked by persistent fatigue, post-exertional malaise, cognitive impairment, and multisystem dysfunction.
Wesam Elremaly, Mohamed Elbakry, Yasaman Vahdani, Anita Franco, Alain Moreau   +4 more
doaj   +1 more source

[Musculoskeletal diseases. A review of musculoskeletal diseases and environment].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1989
The article discusses the remarkably high prevalence of occupationally induced muscle pain and musculoskeletal diseases. The causes of this group of pain/disorders are complex. The increasing economic consequences, and the problems, call for research on practical prophylaxis.
openaire   +1 more source

Beyond Visual Scoring: Computational Computed Tomography Analysis for High‐Resolution Computed Tomography–Based Quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

Arthritis Care &Research, EarlyView.
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil, Tobias Hoffmann, Ulf Teichgräber, Diane Renz, Denise Beckmann, Gunter Wolf, Nicole Schadewaldt, Bianca Lassen‐Schmidt   +7 more
wiley   +1 more source

The primary role of radiological imaging in the diagnosis of rare musculoskeletal diseases. Emphasis on ultrasound

Journal of Ultrasonography, 2019
Objective: In July 2017 a multidisciplinary clinical Center specialized in rare diseases was activated. A rare disease can involve the musculoskeletal system. A multimodality musculoskeletal imaging approach allows for a rapid diagnosis.
Rossi Federica, Martinoli Carlo, Murialdo Giovanni, Schenone Angelo, Grandis Marina, Ferone Diego, Tagliafico Alberto Stefano   +6 more
doaj   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

Arthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

Associations of Frailty With the Risk of Incident Cancer and Cancer‐Related Mortality in Veterans With Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective This study investigated the association between frailty and cancer incidence and mortality in patients with rheumatoid arthritis (RA). It aimed to identify how frailty influences cancer risk and cancer‐specific outcomes. Methods This retrospective cohort study analyzed data from the Veterans’ Affairs Rheumatoid Arthritis Registry (2002–2023).
Bhavik Bansal, Aaron Baraff, Katherine Wysham, James S. Andrews, Bryant R. England, Ted R. Mikuls, Joshua Baker, Kaleb Michaud, Alexa Meara, Una Makris, Carolyn Presley, Ariela Orkaby, Namrata Singh   +12 more
wiley   +1 more source

IMAGING METHODS IN MUSCULOSKELETAL SYSTEM PAIN

, 2022
Musculoskeletal system pain frequency increases with the aging population. Taking a detailed history and physical examination are the most important things for a correct diagnosis. Imaging should be considered as a tool to confirm the diagnosis. A number
Akçiçek, Mehmet
core   +1 more source

Biphasic control of the B cell transcriptome by mTORC1 and GSK3

Cell Reports
Summary: A central question in immune regulation is how cells coordinate transcriptional responses to environmental cues. It remains unclear whether transcriptional regulation is controlled by isolated mechanism or integrated regulatory programs.
Jens Kalchschmidt, Tomoya Kanno, Solji Park, Wendy D. Dubois, Yongbing Zhao, Pawel Trzaskoma, Craig J. Thomas, Louis M. Staudt, John J. O’Shea, Seolkyoung Jung, Rafael Casellas   +10 more
doaj   +1 more source

Automated Hand Flexor Tendon–Thickness Measurement in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) can affect flexor tendons, contributing to hand function problems and reduced quality of life. Tendon changes are currently assessed with ultrasonography and measured manually, a time‐consuming process prone to interobserver variability.
Mark Greveling, Ties van het Erve, Yvette van de Berg, Simon Mastbergen, Julia Spierings   +4 more
wiley   +1 more source