Results 151 to 160 of about 159,003 (269)

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways

Arthritis &Rheumatology, Accepted Article.
Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

Chronic widespread pain prevalence in the general population: a systematic review [PDF]

, 2018
Ablin, Abusdal, Abusdal, Allison, Assumpção, Bannwarth, Barham, Bartley, Beasley, Bender, Benjamin, Bergman, Branco, Braveman, Buskila, Cabral, Carnes, Choudhury, Croft, Croft, Dragioti, Dueñas, Dueñas, Elm, Elzahaf, Fillingim, Flüß, Forseth, Freburger, Gaskin, Gerdle, Hagen, Henschke, Hiller, Hunt, Hurley, Jacobsson, Lee, Lee, Lindell, Macfarlane, Macfarlane, Macfarlane, Macfarlane, Mansfield, Mas, Nicholl, Okifuji, Pang, Papageorgiou, Perrot, Picavet, Pieretti, Ridder De, Rios, Riskowski, Roh, Roth, Santos, Schaefer, Schochat, Schochat, Scudds, Slavin, Soares, Tate, Toda, Topbas, Urwin, Vandenkerkhof, Walker-Bone, White, Wiesenfeld-Hallin, Wolfe, Wolfe   +74 more
core   +2 more sources

Dysregulation of U12‐Type Splicing in Lupus Neutrophils

Arthritis &Rheumatology, Accepted Article.
Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco, Binod Regmi, Carmelo Carmona‐Rivera, Yudong Liu, Xiantao Wang, Philip M. Carlucci, Monica M. Jackson, Zerai Manna, Sarfaraz Hasni, Markus Hafner, Hong‐Wei Sun, Mariana J. Kaplan   +11 more
wiley   +1 more source

Community building through play: Development and design of a board game for review in an undergraduate anatomy course

Anatomical Sciences Education, EarlyView.
Abstract Engaging students and fostering interactions can be a challenge in large enrollment, foundational‐level, undergraduate anatomy classes. Despite the active learning environment of the anatomy laboratory, students often struggle to find study partners or even speak to fellow learners in a large classroom.
Kristin Stover, Vanessa Kruk, Jenna Kuczek   +2 more
wiley   +1 more source

Atypical Visually Guided Precision Grip Control in Middle‐Aged and Older Autistic Adults

Autism Research, EarlyView.
ABSTRACT Sensorimotor impairments are well documented in autism spectrum disorder (ASD). However, little is known about how these difficulties present in middle‐aged and older autistic adults or how they relate to demographic factors and autistic traits.
Zheng Wang, Hang Qu, Danielle Christensen, Hanna M. Gemmell, Ellen M. Parks, Kyla E. Wetherington, Ann‐Marie Orlando, Regilda A. Romero, Bikram Karmakar, David E. Vaillancourt   +9 more
wiley   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

The Effects of Microplastics on Musculoskeletal Disorder; A Narrative Review. [PDF]

Curr Rev Musculoskelet Med
Fusagawa H, Youn A, Wilkerson E, Pandya N, Feeley BT.   +4 more
europepmc   +1 more source

Self-Reported Musculoskeletal Disorder Symptoms among Bus Drivers in the Taipei Metropolitan Area. [PDF]

Int J Environ Res Public Health, 2022
Chen YL, Alexander H, Hu YM.
europepmc   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Prevalence and associated factors of work-related musculoskeletal disorder symptoms amongst emergency medical service workers. [PDF]

Sci Rep
So BCL, Lee EWF, Ng S, Man SS.
europepmc   +1 more source