Results 71 to 80 of about 227,883 (299)

Maintained physical activity and physiotherapy in the management of distal upper limb pain – a protocol for a randomised controlled trial (the Arm Pain Trial) [PDF]

, 2014
Background Upper limb pain is a common cause of disability, demand for health care and lost work time. It is more likely to become persistent if it is accompanied by poor mental health, tendency to somatise, and negative beliefs concerning health and
Jones, Gareth T, Coggon, D., Macfarlane, G.J., Burton, K., Palmer, Keith T., McNamee, P., Jones, Gareth T., Coggon, David, Walker-Bone, Karen, Macfarlane, Gary J, Mertens, K., McCabe, C., McConnachie, A., Macfarlane, Gary J., Palmer, Keith T, Walker-Bone, K., McCabe, Candy, Heine, P.J., Burton, Kim, Mertens, Kathrin, Heine, Peter J, McNamee, Paul, Burton, A. Kim, McConnachie, Alex, Palmer, K. T., Palmer, K.T., Heine, Peter J., Coggon, D. (David), Dr., Jones, G.T.   +28 more
core   +1 more source

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

Data sources for monitoring arthritis and other musculoskeletal conditions [PDF]

, 2014
This report assesses the potential for existing data sources to improve our understanding of arthritis and other musculoskeletal conditions and highlights future opportunities for improving data for monitoring these conditions.

core  

Efficacy of manual therapy on somatic tinnitus dual modulatory factors: a study protocol

Revista Pesquisa em Fisioterapia, 2020
BACKGROUND AND PURPOSE: The literature has shown promising effect of manual therapy in improving the severity of somatic tinnitus.However, no previous study has concentrated onevaluating the combined effect of  temporomandibular joint and  cervical spine
Palak Sharma, Manu Goyal, Saumya Kothiyal   +2 more
doaj   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

Advanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae, Ryan C. Riddle, Zhihua Jiang, Chaeyoung Shin, Min Du, Jun Seok Son   +5 more
wiley   +1 more source

Osteoarthritis: musculoskeletal fact sheet [PDF]

, 2015
This fact sheet summarises information from the AIHW\u27s online musculoskeletal compendium. Summary Osteoarthritis is a degenerative condition mostly affecting the joints such as hips, knees and ankles.
Australian Institute of Health and Welfare
core  

A Modular Variable Stiffness Co‐Bot System Achieving Tasks Flexibility and Contact Compliance

Advanced Science, EarlyView.
Bio‐inspired antagonistic compliance enables a modular rigid‐soft co‐bot platform with variable stiffness for safe human‐robot interaction (HRI): Standardized interfaces support application‐driven configurations with tailored DoFs, workspace, and stiffness range, making the system suited to HRI and low‐volume automation.
Wenlong Gaozhang, Yue Li, Jialei Shi, Yaxi Wang, Kaspar Althoefer, Agostino Stilli, Helge A. Wurdemann   +6 more
wiley   +1 more source

Evaluating the acute impact of diagonal mobilization on knee flexor and extensor strength in young soccer players: a randomized double-blind trial

Biomedical Human Kinetics
Study aim: This study aimed to assess the acute effects of manual therapy, focusing on knee, hip, and sacroiliac joint mobilization (DM), on knee extension (KE) and flexion (KF) strength in young soccer athletes, with the goal of determining the impact ...
Studnicki Rafał, Tomaszewicz Urszula, Hansdorfer-Korzon Rita, Kawczyński Adam   +3 more
doaj   +1 more source

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

Advanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang, Zihao An, Honglu Cai, Congsun Li, Jiaxuan Zou, Wushi Cui, Wentao Chen, Tao Zhang, Shicheng Wang, Zizhan Su, Jian Xiao, Tao Sun, Bin Hu, Min Cheng, Zhongru Gou, Jianbin Xu, An Liu, Haobo Wu   +17 more
wiley   +1 more source

Evolution of Physical Intelligence Across Scales

Advanced Intelligent Discovery, EarlyView.
By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu, Tianyun Huang, Aming Li, Pengyu Lv, Tingting Qin, Wenhui Chen, Hui Wei, Huiling Duan   +7 more
wiley   +1 more source