Results 81 to 90 of about 22,111,810 (336)

Management of work-relevant upper limb disorders: a review [PDF]

, 2008
Background Upper limb disorders (ULDs) are clinically challenging and responsible for considerable work loss. There is a need to determine effective approaches for their management.
A. K. Burton, Abasolo, Alizadehkhaiyat, B. G. Pearce, Baldwin, Beaton, Bonde, Bongers, Buckwalter, Burton, Cheng, Christmansson, Coggon, Coggon, Cole, Coutu, Feuerstein, Feuerstein, Franche, Franche, Greening, Hadler, Hagberg, Harrington, Helliwell, Henderson, Kuijpers, L. C. Bainbridge, L. N. Birrell, Mallen, Marhold, Marsh, Meijer, N. A. S. Kendall, Nash, N  rregaard, Palmer, Piligian, Pransky, Punnett, Roquelaure, Selander, Shaw, Silverstein, Slavin, Staal, Szabo, Szabo, van den Heuvel, van den Heuvel, Van Eerd, Walker-Bone, Walker-Bone, Walker-Bone, Walker-Bone, Walker-Bone, Warren, Williams   +57 more
core   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

A generic musculoskeletal model of the juvenile lower limb for biomechanical analyses of gait

Computer Methods in Biomechanics and Biomedical Engineering, 2020
The aim of this study was to develop a generic musculoskeletal model of a healthy 10-year-old child and examine the effects of geometric scaling on the calculated values of lower-limb muscle forces during gait.
R. Hainisch, A. Kranzl, Yi-Chung Lin, M. Pandy, M. Gfoehler   +4 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

The non-invasive evaluation technique of patellofemoral joint stress: a systematic literature review

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: Patellofemoral joint stress (PFJS) is an important parameter for understanding the mechanism of patellofemoral joint pain, preventing patellofemoral joint injury, and evaluating the therapeutic efficacy of PFP rehabilitation programs.
Baofeng Wang, Zheng Mao, Jiaming Guo, Jin Yang, Shengnian Zhang   +4 more
doaj   +1 more source

Musculoskeletal modelling of an ostrich (Struthio camelus) pelvic limb: influence of limb orientation on muscular capacity during locomotion [PDF]

, 2015
We developed a three-dimensional, biomechanical computer model of the 36 major pelvic limb muscle groups in an ostrich (Struthio camelus) to investigate muscle function in this, the largest of extant birds and model organism for many studies of locomotor
Delp, S L, Hutchinson, J R, Rankin, J W, Rosenbluth, K H, Rubenson, J, Siston, R A   +5 more
core   +2 more sources

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Relationship between joint angle and contact force at the knee during normal gait

Journal of Advanced Mechanical Design, Systems, and Manufacturing
Knee joint contact force is related to knee joint pain and related diseases such as osteoarthritis. Joint loading during gait even on an intact knee may cumulatively lead to the joint diseases. Previous studies on forward dynamics simulation suggest that
Takuya MITANI, Koh INOUE, Satoru TAKAHASHI   +2 more
doaj   +1 more source

The Impact of Hill-Type Actuator Components on the Performance of Reinforcement Learning Controllers to Reverse Upper-Limb Paralysis

IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
Functional electrical stimulation (FES) may allow people who are paralyzed due to spinal cord injuries (SCIs) to regain the ability to move. Deep neural networks (DNNs) trained with reinforcement learning (RL) have been recently explored as a promising ...
Jessica Abreu, Douglas C. Crowder, Robert F. Kirsch   +2 more
doaj   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster, Jae Woo Chung, Maria E. Linn‐Evans, Matthew N. Petrucci, Chiahao Lu, Destiny J. Weaver, Joshua De Kam, Scott E. Cooper, Paul J. Tuite, Aleksandar Videnovic, Michael J. Howell, Colum D. MacKinnon   +11 more
wiley   +1 more source