Advanced Science, EarlyView.SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding +10 more
wiley +1 more source
Epidemiology of musculoskeletal pain in primary care [PDF]
, 2004 Jaime de Inocencio Arocena
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Chronic musculoskeletal pain in neurological practice
, 2021 Д. Х. Хайбуллина +2 more
openalex +1 more source
Advanced Science, EarlyView.A multifunctional injectable microsphere system is fabricated via UV‐assisted microfluidic cross‐linking, integrating nanozyme‐based ROS scavenging, sustained dexamethasone release, and stem cell delivery. Upon IA injection, the microspheres adapt to joint stress, suppress inflammation, and promote cartilage regeneration, offering a minimally invasive ...
Xiaochen Feng +10 more
wiley +1 more source
Interrater Reliability of Performing a Step-by-Step Procedure for Selected Pain Provocation Tests for Hamstrings and Special Tests for Other Lower Extremity Musculoskeletal Injuries [PDF]
Reil Vinard Espino +7 more
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Patterns in the Occurrence and Duration of Musculoskeletal Pain and Interference with Work among Eldercare Workers—A One-Year Longitudinal Study with Measurements Every Four Weeks [PDF]
, 2019 Charlotte Diana Nørregaard Rasmussen +5 more
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Adolescents’ experiences of fluctuating pain in musculoskeletal disorders: a qualitative systematic review and thematic synthesis [PDF]
, 2020 Sonia Khanom +4 more
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Advanced Science, EarlyView.A fully wearable system enables real‐time, dynamic, and accurate monitoring of Young's modulus in multilayer tissues containing deep muscle. It demonstrates high accuracy and robustness across simulations, benchtop validations, and human testing. It quantifies edema severity and tracks muscle stiffness during rest, loaded elbow flexion, rope skipping ...
Zhenning Wang +12 more
wiley +1 more source
Advanced Science, EarlyView.Abstract Building upon the integrative framework of tendinopathy proposed by Gehwolf et al.—which elegantly connects mechanical stress, inflammation, and vascularity—this commentary extends the discussion by introducing novel mechanistic insights and future research directions that move beyond the established triad. A paradigm shift is proposed ...
DuJiang Yang +3 more
wiley +1 more source
Obesity in Young Adulthood: The Role of Physical Activity Level, Musculoskeletal Pain, and Psychological Distress in Adolescence (The HUNT-Study) [PDF]
, 2020 Maren Hjelle Guddal +6 more
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