Results 181 to 190 of about 972,730 (282)

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, Accepted Article.
Background Type I interferonopathies are heterogeneous diseases driven by dysregulated IFN‐I signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. Objective To characterize the clinical, immunological, genetic, molecular profiles of patients with suspected enhanced IFN‐I signaling, and assess ...
Ismail Yaz, Seza Ozen, Hacer N. Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet E. Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet O. Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source

Increased plasma microbial tDR‐1 in at‐risk individuals is associated with decreased conversion to clinical rheumatoid arthritis and reduces an in vitro macrophage type 1 interferon response

Arthritis &Rheumatology, Accepted Article.
Background Microbial small RNAs (sRNAs) can regulate human genes. Higher plasma concentrations of microbial tRNA‐derived RNA‐1 (tDR‐1) were previously associated with lower rheumatoid arthritis (RA) disease activity. This study examined whether tDR‐1 concentrations differ in anti‐cyclic citrullinated peptide‐3 positive (CCP3+) at‐risk individuals (ARI)
Anastasiia Phothisane, Tulsi K Joishy, Carolina Ramirez‐Becerra, Qiong Wu, Jennifer Seifert, Marie L Feser, Jill M Norris, M Kristen Demoruelle, LauraKay Moss, Kevin D Deane, V Michael Holers, Michelle J Ormseth   +11 more
wiley   +1 more source

Integrating yoga into anatomy and clinical medicine education: A holistic approach to learning

Anatomical Sciences Education, EarlyView.
Abstract Anatomical knowledge is fundamental for success in clinical settings. Unfortunately, anatomy education within professional health programs has experienced a continual decrease in contact hours and curricular content over the previous two decades, leading to deficits and potential gaps in anatomical science knowledge.
Dana Rohde, Madeleine E. Norris, Jennifer R. Kinder, Barbie Klein, Derek Harmon   +4 more
wiley   +1 more source

Dynamic Ultrasound Evaluation Supraspinatus Tendon Injuries Using a Pilates Elastic Band

Arthroscopy Techniques, EarlyView.
Abstract Supraspinatus tendon tears are a common cause of shoulder pain and dysfunction. Although magnetic resonance imaging and computed tomography arthrography are still considered the gold standard, ultrasound offers a reliable, accessible, and radiation‐free alternative.
Viet‐Tam Van, Charlotte Vifquain, Romain Nicolle, Nicolas Sans, Nicolas Bonnevialle, Marie Faruch‐Bilfeld   +5 more
wiley   +1 more source

Response to In-Home Virtual Reality Program for Chronic Lower Back Pain: A Randomized Sham-Controlled Effectiveness Trial in a Clinically Severe and Diverse Sample

Mayo Clinic Proceedings: Digital Health
Jesper Knoop, PhD, Syl Slatman, MSc, Bart Staal, PhD   +2 more
doaj   +1 more source

Arthroscopic Anterior Talofibular Ligament Repair Without Anchors for Chronic Lateral Ankle Instability

Arthroscopy Techniques, EarlyView.
Abstract In recent years, arthroscopic anterior talofibular ligament (ATFL) repair techniques have been increasingly used in the treatment of chronic ankle instability. Arthroscopic approaches not only allow for the management of concomitant intra‐articular pathologies but also help minimize wound‐related complications associated with open surgery and ...
Semih Yaş, Orkun Büyüksayın, Muhammet Özsoy, Mustafa Can Erdem, Mehmet Ali Tokgöz, Ulunay Kanatlı   +5 more
wiley   +1 more source

Techniques of Arthroscopic Anterior Syndesmosis Stabilization

Arthroscopy Techniques, EarlyView.
Abstract Ankle sprains are among the most common sports‐related musculoskeletal injuries. Injury to the anterior inferior tibiofibular ligament, resulting in anterior syndesmotic instability, is frequently overlooked and inadequately treated. The purpose of this technical note is to (1) describe clinical examination maneuvers used to assess anterior ...
Dhivakaran Gengatharan, Wayne Yong Xiang Foo, Wen Xian Png, Chong Keen‐Wai, Eric Wei Liang Cher   +4 more
wiley   +1 more source

Multifunctional hyaluronic acid hydrogel integrating exosome‐encapsulating gelatin microspheres accelerates skeletal muscle regeneration via TGF‐β1 activation and enhanced myogenic cell viability

BMEMat, EarlyView.
Schematic illustration of preparation of injectable H/G@Co@miR‐206 hydrogel for efficient skeletal muscle regeneration in cardiotoxin‐induced skeletal muscle injury SD rat model. Abstract The effective treatment of acute skeletal muscle injuries remains challenging, necessitating therapeutic strategies that concurrently reestablish vascular perfusion ...
Zhengzhe Han, Zongyue Li, Ang Li, Zheng Jiang, Saiyu Shi, Zhipeng Wang, Jishizhan Chen, Yun Qian, Yuanyang Gu, Xianyou Zheng   +9 more
wiley   +1 more source

A new paradigm shift in musculoskeletal rehabilitation: why we should exercise the brain? [PDF]

Braz J Phys Ther, 2018
Armijo-Olivo S.
europepmc   +1 more source