Results 201 to 210 of about 1,651,819 (299)

When meta‐analyses mislead: Promises and pitfalls in teratology counselling

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Meta‐analysis has become a central tool for evidence synthesis in clinical teratology, offering the promise of increased statistical power, earlier signal detection and consolidated guidance for teratology counselling. When conducted rigorously and interpreted carefully, pooled analyses can provide clinicians with a structured basis for risk ...
Yusuf Cem Kaplan, Nusret Uysal
wiley   +1 more source

Unsupervised machine learning for multi‐system adverse event pattern detection in pharmacovigilance: A proof‐of‐concept analysis of fluoroquinolone reports in FAERS

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
. Aims Traditional pharmacovigilance detects single drug–event associations but cannot readily characterize multi‐system adverse‐event patterns such as fluoroquinolone‐associated disability. We evaluated unsupervised machine learning for this purpose, using fluoroquinolones as an exemplar.
Niaz Chalabianloo   +3 more
wiley   +1 more source

Therapeutic Fasting as a Novel Approach to Mitigate Musculoskeletal Symptoms in Breast Cancer Patients undergoing Aromatase Inhibitor Therapy: A Feasibility Study Protocol. [PDF]

open access: yesIntegr Cancer Ther
Meyer H   +10 more
europepmc   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

open access: yesBMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu   +9 more
wiley   +1 more source

Grooved Surface of the Obturator Internus Muscle With Two Distinct Adjacent Parts

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The specific anatomical features of the obturator internus, particularly those of its medial surface, remain insufficiently characterized. This study investigated the morphology of the obturator internus muscle by focusing on the shape of its medial surface and potential age‐related changes.
Satoru Muro   +4 more
wiley   +1 more source

Real-world analysis of IL-23 inhibitors in patients with moderate-to-severe psoriasis and early musculoskeletal symptoms. [PDF]

open access: yesDrugs Context
Dattola A   +20 more
europepmc   +1 more source

External Acoustic Meatus Approach for Ultrasonographic Evaluation of the Temporomandibular Joint: An Anatomical Validation and Proof‐of‐Concept Study

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Temporomandibular disorders (TMD) represent a public health problem, affecting 31% of adults and the elderly and 11% of children and adolescents. Interest is growing in using ultrasound to evaluate the temporomandibular joint (TMJ). However, researchers need to standardize a reliable method.
Rossella Alberti   +10 more
wiley   +1 more source

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