Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang +18 more
wiley +1 more source
Advances in applications of low-dimensional piezoelectric materials in musculoskeletal system. [PDF]
Liu L, Li Z, Zhu T, Sun Y, Xu J.
europepmc +1 more source
Orthopedics and Traumatology Skill Matrix for Musculoskeletal System Approach by Medical Graduates. [PDF]
Siqueira EM, Pereira AA, Oliveira IAKM.
europepmc +1 more source
Biohybrid Tendons Enhance the Power‐to‐Weight Ratio and Modularity of Muscle‐Powered Robots
Biohybrid robots powered by skeletal muscle actuators are capable of dynamically adapting to environmental cues. This study takes inspiration from native muscle–tendon architecture by leveraging tough hydrogels as synthetic tendons for muscle actuators to enhance the power‐to‐weight ratio and modularity of biohybrid machines.
Nicolas Castro +11 more
wiley +1 more source
Editorial: The endocrine role of the musculoskeletal system. [PDF]
Zhu S, Storlino G, Kumar S.
europepmc +1 more source
Editorial: Biomechanical and biochemical regulation of the musculoskeletal system. [PDF]
Pan J, Lacroix D, Zhou Y, Wang B.
europepmc +1 more source
Human participants with early‐ or chronic‐stage tendinopathy and healthy controls are investigated using ultrasound Doppler, 3T and 7T MRI, and tendon biopsies. Tendon swelling and hyperperfusion are evident early, while vascular growth and extracellular matrix changes are most pronounced in chronic tendinopathy. Early intervention may provide superior
Max F. R. Merkel +11 more
wiley +1 more source
The Impact of Regular Physical Activity on Children's Health Parameters: A Critical Literature Analysis of Metabolism, the Musculoskeletal System, Respiratory System Diseases, and Neuropsychiatry. [PDF]
Piszka M +8 more
europepmc +1 more source
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló +2 more
wiley +1 more source
Correlation between musculoskeletal system function and pre-depressive states in elderly cancer patients: A single-center cross-sectional study. [PDF]
Zhou YQ +12 more
europepmc +1 more source

