Results 41 to 50 of about 17,611,247 (302)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organisational downsizing and musculoskeletal problems in employees: a prospective study [PDF]

, 2001
Objectives: To study the association between organisational downsizing and subsequent musculoskeletal problems in employees and to determine the association with changes in psychosocial and behavioural risk factors.
Vahtera, J., Ferrie, J.E., Pentti, J., Hemingway, H., Kivimäki, M.   +4 more
core  

Musculoskeletal biomechanics of the shoulder in functional activities [PDF]

, 2013
The aim of this thesis is to determine shoulder function, during specific functional tasks and relate this to key parameters associated with pathology.
Pandis, Petros
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

IMAGING METHODS IN MUSCULOSKELETAL SYSTEM PAIN

, 2022
Musculoskeletal system pain frequency increases with the aging population. Taking a detailed history and physical examination are the most important things for a correct diagnosis. Imaging should be considered as a tool to confirm the diagnosis. A number
Akçiçek, Mehmet
core   +1 more source

Pain and Patient‐Reported Physical Function Did Not Differ Among Body Composition Profiles in Patients With Hip Osteoarthritis

Arthritis Care &Research, EarlyView.
Objective To explore whether higher body fat and lower lean mass are associated with greater pain and worse patient‐reported physical function in individuals with hip osteoarthritis (OA). A secondary aim was to examine whether pain and patient‐reported physical function differ according to four body composition profiles: high body fat, low lean mass ...
Alexandra Ryan, Boliang Wang, Fiona Dobson, Ben Kirk, Travis Haber, Kim L. Bennell, Shirley P. Yu, Kim Allison, Ricardo J. S. Costa, Gabrielle Knox, Michelle Hall   +10 more
wiley   +1 more source

Incidence and prevalence of complaints of the neck and upper extremity in general practice [PDF]

, 2005
OBJECTIVE: To study the incidence and prevalence of neck and upper extremity musculoskeletal complaints in Dutch general practice. METHODS: Data were obtained from the second Dutch national survey of general practice.
Bot, Sandra D.M., Bouter, L. M., Schellevis, F. G., Waal, J.M. van der, Schellevis, F.G., Dekker, J., Van Der Waal, J. M., Bouter, L.M.; id_orcid, Terwee, C. E., Terwee, C.B., Windt, D.A.W.M. van der, Windt - Mens, D.A.W.M. van der, Bouter, L.M., Bot, S.D.M., van der Windt-Mens, D.A.W.M., van der Waal, J.M., Van Der Windt, D. A.W.M.   +16 more
core   +2 more sources

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

An In Vitro Orbital Flow Model to Study Mechanical Loading Effects on Osteoblasts

Biology
Flow induced by an orbital shaker is known to produce shear stress and oscillatory flow, but the utility of this model for studying mechanical loading effects in osteoblasts is not well defined.
Subburaman Mohan, Ritika Surisetty, Chandrasekhar Kesavan   +2 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source