Results 121 to 130 of about 428,318 (395)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Alteration in forward model prediction of sensory outcome of motor action in Focal Hand Dystonia

open access: yesFrontiers in Human Neuroscience, 2013
Focal hand dystonia in musicians is a movement disorder affecting highly trained movements. Rather than being a pure motor disorder related to movement execution only, movement planning, error prediction and sensorimotor integration are also impaired ...
André eLee   +3 more
doaj   +1 more source

Health problems of orchestral musicians from a life-span perspective

open access: yes, 2018
The profession of orchestral musician is often linked to musculoskeletal problems, hearing disorders, and struggles with stage fright. However, data on the prevalence of physical problems are very divergent because of different research methods and ...
Heiner Gembris, Andreas Heye, A. Seifert
semanticscholar   +1 more source

Passion at the heart of musicians’ well-being

open access: yesPsychology of Music, 2018
This article proposes that passion for music is an essential element in explaining the well-being of musicians. Based on the PERMA model of well-being and on research on passion for music, this article posits that being passionate about music, and more ...
Arielle Bonneville-Roussy, R. Vallerand
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Broadway hitmen [1st keyboard] [PDF]

open access: yes, 2018
1st Keyboard in the orchestra for Broadway Hitmen, performed 18-21 October 2018 at Clarence Street Theatre, Hamilton, New Zealand, featuring professional singers and musicians from Hamilton and New Zealand. The show was positively received by audiences;
Braae, Nick
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Prevalence of musculoskeletal disorders in symphonic orchestra’s musicians: A cross-sectional study in Italy [PDF]

open access: yesGIornale Italiano di Psicologia e Medicina del Lavoro
Introduction: This study aims to investigate the incidence and characteristics of musculoskeletal disorders among professional musicians, exploring the correlations between the use of different musical instruments and the onset of such pathologies ...
Giuseppe TAINO   +6 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Changing the Beat: A Study of the Worklife of Jazz Musicians, Volume II: American Federation of Musicians Survey Results [PDF]

open access: yes, 2003
Examines the worklife of jazz musicians in New York, Detroit, San Francisco and New Orleans. Prepared by the Research Center for Arts and Culture, under a cooperative agreement with the NEA and the San Francisco Study ...
Joan Jeffri
core  

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